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  • Design, Synthesis and Biological Evaluation of 7 Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors 

    Andreev, Stanislav,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Pantsar, Tatu,Department of Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076 Tübingen, Germany; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Ansideri, Francesco,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Kudolo, Mark,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Forster, Michael,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Schollmeyer, Dieter,Department of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, 55099 Mainz, Germany; Laufer, Stefan,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Koch, Pierre,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Department of Pharmaceutical / Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany (2019-05-22)
    The dataset related to the publication: Andreev et al.Design, Synthesis and Biological Evaluation of 7 Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors. The files include: 1) Movies of ...
  • Pyridinylimidazoles as dual glycogen synthase kinase 3ß/p38[alpha] mitogen-activated protein kinase inhibitors 

    Heider, Fabian; Ansideri, Francesco; Tesch, Roberta; Pantsar, Tatu; Haun, Urs; Döring, Eva; Kudolo, Mark; Poso, Antti; Albrecht, Wolfgang; Laufer, Stefan A; Koch, Pierre (Elsevier BVRanska, 2019)
    Compounds simultaneously inhibiting two targets that are involved in the progression of the same complex disease may exhibit additive or even synergistic therapeutic effects. Here we unveil 2,4,5-trisubstituted imidazoles ...
  • Is stump harvesting for bioenergy production socially acceptable in Finland? 

    Rahman, Abul; Khanam, Tahamina; Pelkonen, Paavo (Elsevier BV, 2019)
    Stump wood is used to produce electricity and heat, especially in Finland, where biomass-based energy plays a major role. This study, which aims to investigate the social acceptance of stump harvesting for bioenergy ...
  • Beaming the second harmonic generation from a double layered bull's eye structure 

    Li, Fangfang; Li, Peng; Kang, Guoguo (Elsevier BVAlankomaat, 2019)
    We report on a numerical investigation of the beaming effect of second harmonic generation (SHG) from a double layered bull’s eye structure where a nanobowtie is sandwiched between. Both linear and nonlinear responses were ...
  • Peer review assessment of originality in tourism journals: critical perspective of key gatekeepers 

    Rodríguez Sánchez, Isabel; Makkonen, Teemu; Williams, Allan M (Elsevier BV, 2019)
    Originality is an essential element of academic research and the peer review system plays a key gatekeeping role in its acceptance. However, there is no consensus as to the precise definition of the concept, its measurement ...

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