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Now showing items 487-506 of 2431

    • Daily Life on Wheels: Global (Car) Cultures and Local Living 

      Hämeenaho, Pilvi (Yhdysvallat (USA), 2019)
      Ordinary tasks, like working, taking part in social events, leisure time activities, and consumerism create a need to move. The location of residence determines the means and ways of performing these activities. When ...

    • Dark chocolate and reduced snack consumption in mildly hypertensive adults: an intervention study 

      Koli, Raika; Köhler, Klaus; Tonteri, Elina; Peltonen, Juha; Tikkanen, Heikki; Fogelholm, Mikael (BioMed Central, 2015-08-22)
      Background Several studies have shown that cocoa and cocoa-containing foods have the potential to lower blood pressure and improve endothelial function. Most of the studies reporting the beneficial effects of dark chocolate ...

    • Data analytics approach to create waste generation profiles for waste management and collection 

      Niska, Harri; Serkkola, Ari (Elsevier BVAlankomaat, 2018)
      Extensive monitoring data on waste generation is increasingly collected in order to implement cost-efficient and sustainable waste management operations. In addition, geospatial data from different registries of the society ...

    • Data on synthesis of methylene bisphosphonates and screening of their inhibitory activity towards HIV reverse transcriptase 

      Yanvarev DV; Korovina AN; Usanov NN; Khomich OA; Vepsäläinen Jouko; Puljula Elina; Kukhanova MK; Kochetkov SN (Elsevier Inc., 2016)
      Inorganic pyrophosphate (PPi) mimetics designed on a basis of methylenediphosphonic acid backbone are promising inhibitors of two key HIV replication enzymes, IN [1] and RT [2]. Herein, we present chemical synthesis of ...

    • Data-Driven Differential Diagnosis of Dementia Using Multiclass Disease State Index Classifier 

      Tolonen, Antti; Rhodius-Meester, Hanneke F M; Bruun, Marie; Koikkalainen, Juha; Barkhof, Frederik; Lemstra, Afina W; Koene, Teddy; Scheltens, Philip; Teunissen, Charlotte E; Tong, Tong; Guerrero, Ricardo; Schuh, Andreas; Ledig, Christian; Baroni, Marta; Rueckert, Daniel; Soininen, Hilkka; Remes, Anne M; Waldemar, Gunhild; Hasselbalch, Steen G; Mecocci, Patrizia; van der Flier, Wiesje M; Lotjönen, Jyrki (Frontiers Media SA, 2018)
      Clinical decision support systems (CDSSs) hold potential for the differential diagnosis of neurodegenerative diseases. We developed a novel CDSS, the PredictND tool, designed for differential diagnosis of different types ...

    • The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project 

      Hudson Lawrence N; Newbold Tim; Contu Sara; Hill Samantha LL; Lysenko Igor; De Palma Adriana; Phillips Helen RP; Alhusseini Tamera I; Bedford Felicity E; Bennet Dominic J; Booth Hollie; Burton Victoria J; Chng Charlotte WT; Choimes Argyrios; Correia David LP; Day Julie; Echeverría-Londoño Susy; Emerson Susan R; Gao Di; Garon Morgan et al. (Wiley-BlackwellYhdysvallat (USA), 2017)
      The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)—has collated from published studies a large, reasonably representative database of comparable samples ...

    • Decline of genetic diversity in ancient domestic stallions in Europe 

      Wutke, S; Sandoval-Castellanos, E; Benecke, N; Döhle, HJ; Friederich, S; Gonzalez, J; Hofreiter, M; Lõugas, L; Magnell, O; Malaspinas, AS; Morales-Muñiz, A; Orlando, L; Reissmann, M; Trinks, A; Ludwig, A (American Association for the Advancement of Science (AAAS), 2018)
      Present-day domestic horses are immensely diverse in their maternally inherited mitochondrial DNA, yet they show very little variation on their paternally inherited Y chromosome. Although it has recently been shown that Y ...

    • Decompositions of Nakano norms by ODE techniques 

      Talponen, Jarno (Finnish Academy of Science and LettersSuomi, 2018)
      We study decompositions of Nakano type varying-exponent Lebesgue norms and spaces. These function spaces are represented here in a natural way as tractable varying-exponent ℓp sums of projection bands. The main results ...

    • Decrease of Population Divergence in Eurasian Perch (Perca fluviatilis) in Browning Waters: Role of Fatty Acids and Foraging Efficiency 

      Scharnweber Kristin; Strandberg Ursula; Karlsson Konrad; Eklöv Peter (Public Library of Science (PLoS), 2016)
      Due to altered biogeochemical processes related to climate change, highly colored dissolved organic carbon (DOC) from terrestrial sources will lead to a water “brownification” in many freshwater systems of the Northern ...

    • Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma 

      Poukka, M; Bykachev, A; Siiskonen, H; Tyynelä-Korhonen, K; Auvinen, P; Pasonen-Seppänen, S; Sironen, R (BioMed Central Ltd., 2016)
      Background Hyaluronan is a large extracellular matrix molecule involved in several biological processes such as proliferation, migration and invasion. In many cancers, hyaluronan synthesis is altered, which implicates ...

    • Decreased plasma C-reactive protein levels in APOE E 4 allele carriers 

      Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko (Wiley, 2018)
      Objective Apolipoprotein E (APOE) ε4 allele is a well‐established risk factor in Alzheimer's disease (AD). Here, we assessed the effects of APOE polymorphism on cardiovascular, metabolic, and inflammation‐related parameters ...

    • Deep convolutional neural networks for estimating porous material parameters with ultrasound tomography 

      Lähivaara, Timo; Kärkkäinen, Leo; Huttunen, Janne MJ; Hesthaven, Jan S (Acoustical Society of America (ASA), 2018)
      The feasibility of data based machine learning applied to ultrasound tomography is studied to estimate water-saturated porous material parameters. In this work, the data to train the neural networks is simulated by solving ...

    • Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility 

      Kyyriäinen, J; Bolkvadze, T; Koivisto, H; Lipponen, A; Pérez, LO; Ekolle Ndode-Ekane, X; Tanila, H; Pitkänen, A (Elsevier BVAlankomaat, 2019)
      Extracellular proteolysis initiated by the binding of urokinase-type plasminogen activator (uPA) to its receptor (uPAR) regulates the development of inhibitory neuronal circuits in the cerebral cortex and tissue remodeling ...

    • Defining the risk factors for acute, subacute and chronic cough: a cross-sectional study in a Finnish adult employee population . 

      Lätti, Anne M; Pekkanen, Juha; Koskela, Heikki O (BMJ, 2018)
      Objectives Chronic cough is linked to various long-standing risk factors like asthma, chronic rhinitis and oesophageal reflux disease. On the contrary, acute and subacute cough are usually considered to be caused by acute ...

    • Degradation potentials of dissolved organic carbon (DOC) from thawed permafrost peat 

      Selvam BP; Lapierre JF; Guillemette F; Voigt C; Lamprecht RE; Biasi C; Christensen TR; Martikainen PJ; Berggren M (Springer Nature, 2017)
      Global warming can substantially affect the export of dissolved organic carbon (DOC) from peat-permafrost to aquatic systems. The direct degradability of such peat-derived DOC, however, is poorly constrained because previous ...

    • Degrowth in city planning 

      Lehtinen, Ari Aukusti (Fennia - International Journal of GeographySuomi, 2018)
      This paper summarises the key arguments of degrowth thinking and examines their validity in a city planning setting. The paper argues that much of the reorientation work that is necessary to meet the goals of international ...

    • Delayed, distant skin lesions after transcranial direct current stimulation 

      Kortteenniemi, Aaron; Lehto, SoiliM; Javadi, Amir-Homayoun (Elsevier BVYhdysvallat (USA), 2018)

    • Delivering a one-stop, integrated, and patient-centered service for patients with rheumatic diseases 

      Väre Paula; Nikiphorou Elena; Hannonen Pekka; Sokka Tuulikki (SAGE Publications, 2016)
      Objective: To describe a one-stop, integrated rheumatology service and assess patient satisfaction. Methods: A descriptive report and patient satisfaction survey of a rheumatology clinic model first developed in 1996 ...

    • Dental and periodontal health in Finnish adults in 2000 and 2011 

      Suominen, AL; Varsio, S; Helminen, S; Nordblad, A; Lahti, S; Knuuttila, M (Informa UK Limited, 2018)
      Objective: We assessed dental and periodontal health in adults aged ≥30 years living in southern and northern Finland as part of the Health 2000/2011 Surveys (BRIF8901). Material and methods: Clinical findings in 2000 ...

    • Dependence of welding fume particle toxicity on electrode type and current intensity assessed by microalgae growth inhibition test 

      Kirichenko, K; Zakharenko, A; Pikula, K; Chaika, V; Markina, Z; Orlova, T; Medvedev, S; Waissi, G; Kholodov, A; Tsatsakis, A; Golokhvast, K (Elsevier BV, 2019)
      Welding fumes are a major source of metal oxide particles, ozone, carbon monoxide, carbon dioxide, nitrogen oxides, and many other toxic substances. Hazardous properties and the level of toxicity of welding fumes depend ...