Now showing items 600-619 of 2847

    • Delivering a one-stop, integrated, and patient-centered service for patients with rheumatic diseases 

      Väre Paula; Nikiphorou Elena; Hannonen Pekka; Sokka Tuulikki (SAGE Publications, 2016)
      Objective: To describe a one-stop, integrated rheumatology service and assess patient satisfaction. Methods: A descriptive report and patient satisfaction survey of a rheumatology clinic model first developed in 1996 ...
    • Dental and periodontal health in Finnish adults in 2000 and 2011 

      Suominen, AL; Varsio, S; Helminen, S; Nordblad, A; Lahti, S; Knuuttila, M (Informa UK Limited, 2018)
      Objective: We assessed dental and periodontal health in adults aged ≥30 years living in southern and northern Finland as part of the Health 2000/2011 Surveys (BRIF8901). Material and methods: Clinical findings in 2000 ...
    • Dependence of welding fume particle toxicity on electrode type and current intensity assessed by microalgae growth inhibition test 

      Kirichenko, K; Zakharenko, A; Pikula, K; Chaika, V; Markina, Z; Orlova, T; Medvedev, S; Waissi, G; Kholodov, A; Tsatsakis, A; Golokhvast, K (Elsevier BV, 2019)
      Welding fumes are a major source of metal oxide particles, ozone, carbon monoxide, carbon dioxide, nitrogen oxides, and many other toxic substances. Hazardous properties and the level of toxicity of welding fumes depend ...
    • Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model 

      Roginska Dorota; Kawa Milosz P; Pius-Sadowska Ewa; Lejkowska Renata; Luczkowska Karolina; Wiszniewska Barbara; Kaarniranta Kai; Paterno Jussi J; Schmidt Christian A; Machalinski Boguslaw; Machalinska Anna (Hindawi Limited, 2017)
      The aim of the study was to investigate the influence of complement component C3 global depletion on the biological structure and function of the aged retina. In vivo morphology (OCT), electrophysiological function (ERG), ...
    • Deposition of respiratory virus pathogens on frequently touched surfaces at airports 

      Ikonen, N; Savolainen-Kopra, C; Enstone, JE; Kulmala, I; Pasanen, P; Salmela, A; Salo, S; Nguyen-Van-Tam, JS; Ruutu, P (Springer Nature America, Inc, 2018)
      Background International and national travelling has made the rapid spread of infectious diseases possible. Little information is available on the role of major traffic hubs, such as airports, in the transmission of ...
    • Depression is associated with the long-term outcome of lumbar spinal stenosis surgery: a 10-year follow-up study 

      Tuomainen, I; Pakarinen, M; Aalto, T; Sinikallio, S; Kröger, H; Viinamäki, H; Airaksinen, O (Elsevier BV, 2018)
      Background Context Depression is associated with greater postoperative disability in patients with lumbar spinal stenosis (LSS). No previous studies have reported the association in a 10-year follow-up. Purpose To ...
    • Deregulation of the non-coding genome in leukemia 

      Teppo Susanna; Heinäniemi Merja; Lohi Olli (Informa UK Limited, 2017)
      Methodological advances that allow deeper characterization of non-coding elements in the genome have started to reveal the full spectrum of deregulation in cancer. We generated an inducible cell model to track transcriptional ...
    • Derivatives of Inner Functions in Bergman Spaces Induced by Doubling Weights 

      Pérez-González Fernando; Rättyä Jouni; Reijonen Atte (Finnish Academy of Science and LettersSuomi, 2017)
    • Desert plant bacteria reveal host influence and beneficial plant growth properties 

      Eida, Abdul Aziz; Ziegler, Maren; Lafi, Feras F; Michell, Craig T; Voolstra, Christian R; Hirt, Heribert; Saad, Maged M (Public Library of Science (PLoS)Yhdysvallat (USA), 2018)
      Deserts, such as those found in Saudi Arabia, are one of the most hostile places for plant growth. However, desert plants are able to impact their surrounding microbial community and select beneficial microbes that promote ...
    • Design of 2D-nanocrystals in water: Preparation, structure and functionalization 

      Aslanov, L; Zakharov, V; Paseshnichenko, K; Yatsenko, A; Orekhov, A; Tafeenko, V; Chernyshev, V (Walter de Gruyter GmbH, 2018)
      A new method for synthesis of 2D nanocrystals in water was proposed. The use of perfluorothiophenolate ions as surfactant allowed us to produce 2D single-crystal nanosheets of CaS at pH=9 and flat nanocrystals of PbS at ...
    • Design Science Research Strengthened: Integrating Co-creation and Co-design 

      Suero Montero, Calkin; Kapinga, Alsen Florian (Springer International Publishing, 2019)
      Design science research (DSR) is a well-known methodology that uses design as a tool for the development of both practical research resulting in an artefact solution, and theoretical scientific knowledge resulting in ...
    • Design, development, and evaluation of a mobile learning application for computing education 

      Oyelere SS; Suhonen J; Wajiga GM; Sutinen E (Springer Nature, 2017)
      The study focused on the application of the design science research approach in the course of developing a mobile learning application, MobileEdu, for computing education in the Nigerian higher education context. MobileEdu ...
    • Design, Synthesis and Biological Evaluation of 7 Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors 

      Andreev, Stanislav,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Pantsar, Tatu,Department of Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076 Tübingen, Germany; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Ansideri, Francesco,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Kudolo, Mark,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Forster, Michael,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Schollmeyer, Dieter,Department of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, 55099 Mainz, Germany; Laufer, Stefan,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Koch, Pierre,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Department of Pharmaceutical / Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany (2019-05-22)
      The dataset related to the publication: Andreev et al.Design, Synthesis and Biological Evaluation of 7 Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors. The files include: 1) Movies of ...
    • Design, Synthesis and Biological Evaluation of 7-Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors 

      Andreev, Stanislav,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Pantsar, Tatu,Department of Internal Medicine VIII, University Hospital Tübingen, Otfried-Müller-Str. 14, 72076 Tübingen, Germany; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland; Ansideri, Francesco,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Kudolo, Mark,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Forster, Michael,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Schollmeyer, Dieter,Department of Organic Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10-14, 55099 Mainz, Germany; Laufer, Stefan,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Koch, Pierre,Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany; Department of Pharmaceutical / Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany (2019-06-18)
      The dataset related to the publication: Andreev et al.Design, Synthesis and Biological Evaluation of 7 Chloro-9H-pyrimido[4,5-b]indole-based Glycogen synthase kinase-3β inhibitors. The files include: 1) Movies of ...
    • Design, Synthesis, and Biological Evaluation of 2,4-Dihydropyrano[2,3-c]pyrazole Derivatives as Autotaxin Inhibitors 

      Pantsar T; Singha P; Nevalainen TJ; Koshevoy I; Leppänen J; Poso A; Niskanen JMA; Pasonen-Seppänen S; Savinainen JR; Laitinen T; Laitinen JT (Elsevier BV, 2017)
      Inhibition of Autotaxin (ATX) is a potential treatment strategy for several diseases, including tumors with elevated ATX-lysophosphatidic acid (LPA) signaling. Combining structure-based virtual screening together with hen ...
    • Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin 

      Näkki, S; Wang, JT; Wu, J; Fan, L; Rantanen, J; Nissinen, T; Kettunen, MI; Backholm, M; Ras, RHA; Al-Jamal, KT; Lehto, VP; Xu, W (Elsevier BVAlankomaat, 2019)
      The inability of traditional chemotherapeutics to reach cancer tissue reduces the treatment efficacy and leads to adverse effects. A multifunctional nanovector was developed consisting of porous silicon, superparamagnetic ...
    • Detailed point cloud data on stem size and shape of Scots pine trees 

      Saarinen, Ninni,University of Helsinki, University of Eastern Finland; Kankare, Ville,University of Eastern Finland, University of Helsinki; Yrttimaa, Tuomas,University of Eastern Finland; Viljanen, Niko,Finnish Geospatial Research Institute, Aalto University; Honkavaara, Eija,Finnish Geospatial Research Institute; Holopainen, Markus,University of Helsinki; Hyyppä, Juha,Finnish Geospatial Research Institute; Huuskonen, Saija,Natural Resources Institute Finland; Hynynen, Jari,Natural Resources Institute Finland; Vastaranta, Mikko,University of Eastern Finland (2020-03-09)
      This data set is comprised of three packed zip files and they include text files of 3D information from terrestrial laser scanning (TLS) and aerial imagery from unmanned aerial vehicle (UAV) from individual Scots pine trees ...
    • Detecting and characterizing downed dead wood using terrestrial laser scanning 

      Yrttimaa, Tuomas; Saarinen, Ninni; Luoma, Ville; Tanhuanpää, Topi; Kankare, Ville; Liang, Xinlian; Hyyppä, Juha; Holopainen, Markus; Vastaranta, Mikko (Elsevier BVAlankomaat, 2019)
      Dead wood is a key forest structural component for maintaining biodiversity and storing carbon. Despite its important role in a forest ecosystem, quantifying dead wood alongside standing trees has often neglected when ...
    • Detecting Emotions in Students' Generated Content: An Evaluation of EmoTect System 

      Kolog, Emmanuel Awuni (Springer Singapore, 2018)
      In this paper, an e-counselling system for automatic detection of emotion in text is evaluated by comparing with two of text classifiers implemented in WEKA machine learning software. A support vector machine classifier ...