Browsing by Author "Brenner H"
Now showing items 1-2 of 2
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Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium
Barrdahl M; Rudolph A; Hopper JL; Southey MC; Broeks A; Fasching PA; Beckmann MW; Gago-Dominguez M; Castelao JE; Guénel P; Truong T; Bojesen SE; Gapstur SM; Gaudet MM; Brenner H; Arndt V; Brauch H; Hamann U; Mannermaa A; Lambrechts D et al (Wiley-Blackwell, 2017)Investigating the most likely causal variants identified by fine-mapping analyses may improve the power to detect gene–environment interactions. We assessed the interplay between 70 single nucleotide polymorphisms identified ...info:eu-repo/semantics/article
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TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer
Fagerholm R; Khan S; Schmidt MK; García-Closas M; Heikkilä P; Saarela J; Beesley J; Jamshidi M; Aittomäki K; Liu J; Ali HR; Andrulis IL; Beckmann MW; Behrens S; Blows FM; Brenner H; Chang-Claude J; Couch FJ; Czene K; Fasching PA; et al [Incl Kosma V-M] (Impact Journals, LLC, 2017)TP53 overexpression is indicative of somatic TP53 mutations and associates with aggressive tumors and poor prognosis in breast cancer. We utilized a two-stage SNP association study to detect variants associated with breast ...info:eu-repo/semantics/article