Now showing items 1-4 of 4

    • Factors associated with staying or leaving a dentist leader's position - a qualitative study 

      Tuononen, Tiina; Suominen, Anna Liisa; Lammintakanen, Johanna (Springer Science + Business Media, 2016)
      Background Leadership and leaders have important roles today, possibly even more so in the future, since major organizational changes will occur throughout the health care sector. Tomorrow’s leaders will need to be ...

    • Healthy ageing through internet counselling in the elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment 

      Richard, E; Jongstra, S; Soininen, H; Brayne, C; Moll van Charante, EP; Meiller, Y; van der Groep, B; Beishuizen, CR; Mangialasche, F; Barbera, M; Ngandu, T; Coley, N; Guillemont, J; Savy, S; Dijkgraaf, MG; Peters, RJ; van Gool, WA; Kivipelto, M; Andrieu, S (BMJ, 2016)
      Introduction Cardiovascular disease and dementia share a number of risk factors including hypertension, hypercholesterolaemia, smoking, obesity, diabetes and physical inactivity. The rise of eHealth has led to increasing ...

    • Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses 

      Aho, Vilma; Ollila, Hanna M; Kronholm, Erkki; Bondia-Pons, Isabel; Soininen, Pasi; Kangas, Antti J; Hilvo, Mika; Seppälä, Ilkka; Kettunen, Johannes; Oikonen, Mervi; Raitoharju, Emma; Hyötyläinen, Tuulia; Kähönen, Mika; Viikari, Jorma S; Härmä, Mikko; Sallinen, Mikael; Olkkonen, Vesa M; Alenius, Harri; Jauhiainen, Matti; Paunio, Tiina et al (Nature Publishing Group, 2016)
      Sleep loss and insufficient sleep are risk factors for cardiometabolic diseases, but data on how insufficient sleep contributes to these diseases are scarce. These questions were addressed using two approaches: an experimental, ...

    • Sirtuin functions and modulation: from chemistry to the clinic 

      Carafa, Vincenzo; Rotili, Dante; Forgione, Mariantonietta; Cuomo, Francesca; Serretiello, Enrica; Hailu, Gebremedhin S; Jarho, Elina; Lahtela-Kakkonen, Maija; Mai, Antonello; Altucci, Lucia (Springer Nature, 2016)
      Sirtuins are NAD+-dependent histone deacetylases regulating important metabolic pathways in prokaryotes and eukaryotes and are involved in many biological processes such as cell survival, senescence, proliferation, apoptosis, ...