Browsing by Author "Jukkola-Vuorinen A"
Now showing items 1-2 of 2
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Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility
Mantere T; Tervasmäki A; Nurmi A; Rapakko K; Kauppila S; Tang J; Schleutker J; Kallioniemi A; Hartikainen JM; Mannermaa A; Nieminen P; Hanhisalo R; Lehto S; Suvanto M; Grip M; Jukkola-Vuorinen A; Tengström M; Auvinen P; Kvist A; Borg Å et al (Springer Nature, 2017)Several known breast cancer susceptibility genes encode proteins involved in DNA damage response (DDR) and are characterized by rare loss-of-function mutations. However, these explain less than half of the familial cases. ...info:eu-repo/semantics/article
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CHEK2 c.1100delC mutation is associated with an increased risk for male breast cancer in Finnish patient population
Hallamies S; Pelttari LM; Poikonen-Saksela P; Jekunen A; Jukkola-Vuorinen A; Auvinen P; Blomqvist C; Aittomäki K; Mattson J; Nevanlinna H (Springer Nature, 2017)Background Several susceptibility genes have been established for female breast cancer, of which mutations in BRCA1 and especially in BRCA2 are also known risk factors for male breast cancer (MBC). The role of other breast ...info:eu-repo/semantics/article