Browsing by Author "Kaarniranta K"
Now showing items 1-4 of 4
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Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells
Juuti-Uusitalo K; Koskela A; Kivinen N; Viiri J; Hyttinen JMT; Reinisalo M; Koistinen A; Uusitalo H; Sinha D; Skottman H; Kaarniranta K (MDPI AG, 2017)The impairment of autophagic and proteasomal cleansing together with changes in pigmentation has been documented in retinal pigment epithelial (RPE) cell degeneration. However, the function and co-operation of these ...info:eu-repo/semantics/article
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Contacting co-culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells
Skottman H; Muranen J; Lähdekorpi H; Pajula E; Mäkelä K; Koivusalo L; Koistinen A; Uusitalo H; Kaarniranta K; Juuti-Uusitalo K (Elsevier BV, 2017)Here we evaluated the effects of human retinal microvascular endothelial cells (hREC) on mature human embryonic stem cell (hESC) derived retinal pigment epithelial (RPE) cells. The hESC-RPE cells (Regea08/017, Regea08/023 ...info:eu-repo/semantics/article
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Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity
Salminen A; Kaarniranta K; Kauppinen A (Elsevier BV, 2017)FGF21 is a multifunctional metabolic and stress hormone which is normally expressed in liver but cellular stress, e.g. mitochondrial or endoplasmic reticulum (ER) stress, can induce its expression and subsequent secretion ...info:eu-repo/semantics/article
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Outcome of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in real-life setting
Kataja M; Hujanen P; Huhtala H; Kaarniranta K; Tuulonen A; Uusitalo-Jarvinen H (BMJ, 2018)Aims To evaluate outcome of anti-vascular endothelial growth factor (VEGF) therapy for the treatment of neovascular age-related macular degeneration (nAMD) in the real-life setting and to compare incidence of ocular serious ...info:eu-repo/semantics/article