Now showing items 1-2 of 2

    • Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer 

      Jarvis D; Mitchell JS; Law PJ; Palin K; Tuupanen S; Gylfe A; Hänninen UA; Cajuso T; Tanskanen T; Kondelin J; Kaasinen E; Sarin A-P; Kaprio J; Eriksson JG; Rissanen H; Knekt P; Pukkala E; Jousilahti P; Salomaa V; Ripatti S; Palotie A; Järvinen H; Renkonen-Sinisalo L; Lepistö A; Böhm J; Meklin J-P; Al-Tassan NA; Palles C; Martin L; Barclay E; Farrington SM; Timofeeva MN; Meyer BF; Wakil SM; Campbell H; Smith C.G; Idziaszczyk S; Maughan TS; Kaplan R; Kerr R; Kerr D; Buchanan DD; Win AK; Hopper JL; Jenkins MA; Lindor NM; Newcomb PA (Cancer Research UK, 2016-06-23)
      Background: Observational studies have associated adiposity with an increased risk of colorectal cancer (CRC). However, such studies do not establish a causal relationship. To minimise bias from confounding we performed ...
    • Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis 

      May-Wilson S; Sud A; Law PJ; Palin K; Tuupanen S; Gylfe A; Hänninen UA; Cajuso T; Tanskanen T; Kondelin J; Kaasinen E; Sarin AP; Eriksson JG; Rissanen H; Knekt P; Pukkala E; Jousilahti P; Salomaa V; Ripatti S; Palotie A; Renkonen-Sinisalo L; Lepistö A; Böhm J; Mecklin JP; Al-Tassan NA; Palles C; Farrington SM; Timofeeva MN; Meyer BF; Wakil SM; Campbell H; Smith CG; Idziaszczyk S; Maughan TS; Fisher D; Kerr R; Kerr D; Passarelli MN; Figueiredo JC; Buchanan DD; Win AK; Hopper JL; Jenkins MA; Lindor NM; Newcomb PA; Gallinger S; Conti D; Schumacher F; Casey G; Aaltonen LA; Cheadle JP; et al (Elsevier BV, 2017)
      Background While dietary fat has been established as a risk factor for colorectal cancer (CRC), associations between fatty acids (FAs) and CRC have been inconsistent. Using Mendelian randomisation (MR), we sought to ...