Browsing by Author "Kuosmanen, Suvi M"

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    • The Effects of Sequence Variation on Genome-wide NRF2 Binding - New Target Genes and Regulatory SNPs 

      Kuosmanen, Suvi M; Viitala, Sari; Laitinen, Tuomo; Peräkylä, Mikael; Pölönen, Petri; Kansanen, Emilia; Leinonen, Hanna; Raju, Suresh; Wienecke-Baldacchino, Anke; Närvänen, Ale; Poso, Antti; Heinäniemi, Merja; Heikkinen, Sami; Levonen, Anna-Liisa (Oxford University Press, 2016)
      Transcription factor binding specificity is crucial for proper target gene regulation. Motif discovery algorithms identify the main features of the binding patterns, but the accuracy on the lower affinity sites is often ...
      info:eu-repo/semantics/article