Browsing by Author "Ma, Lijiang"

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    • FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells 

      Wong, Doris; Auguste, Gaelle; Lino Cardenas, Christian L; Turner, Adam W; Chen, Yixuan; Song, Yipei; Ma, Lijiang; Perry, R Noah; Aherrahrou, Redouane; Kuppusamy, Maniselvan; Yang, Chaojie; Mosquera, Jose Verdezoto; Dube, Collin J; Khan, Mohammad Daud; Palmore, Meredith; Kalra, Jaspreet; Kavousi, Maryam; Peyser, Patricia A; Matic, Ljubica; Hedin, Ulf; Manichaikul, Ani; Sonkusare, Swapnil K; Civelek, Mete; Kovacic, Jason C; Bjorkegren, Johan LM; Malhotra, Rajeev; Miller, Clint L (The American Heart Association, 2023)
      Background: Genome-wide association studies have identified hundreds of loci associated with common vascular diseases, such as coronary artery disease, myocardial infarction, and hypertension. However, the lack of mechanistic ...

    • Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells 

      Aherrahrou, Rédouane; Guo, Liang; Nagraj, Vijay Peter; Aguhob, Aaron Andrew; Hinkle, Jameson; Chen, Lisa; Soh, Joon Yuhl; Lue, Dillon; Alencar, Gabriel F; Boltjes, Arjan; van der Laan, Sander W; Farber, Emily; Fuller, Daniela; Anane-Wae, Rita; Akingbesote, Ngozi D; Manichaikul, Ani W; Ma, Lijiang; Kaikkonen, Minna U; Björkegren, Johan LM; Önengüt-Gümüscu, Suna; et al. (Ovid Technologies (Wolters Kluwer Health), 2020)
      Rationale: Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Recent genome-wide association studies revealed 163 loci associated with CAD. However, the precise molecular mechanisms by ...
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    • Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes 

      Aherrahrou, Rédouane; Lue, Dillon; Perry, R Noah; Aberra, Yonathan Tamrat; Khan, Mohammad Daud; Soh, Joon Yuhl; Örd, Tiit; Singha, Prosanta; Yang, Qianyi; Gilani, Huda; Benavente, Ernest Diez; Wong, Doris; Hinkle, Jameson; Ma, Lijiang; Sheynkman, Gloria M; den Ruijter, Hester M; Miller, Clint L; Björkegren, Johan LM; Kaikkonen, Minna U; Civelek, Mete (American Heart Association, Inc, 2023)
      Background: Coronary artery disease (CAD) is the leading cause of death worldwide. Recent meta-analyses of genome-wide association studies have identified over 175 loci associated with CAD. The majority of these loci are ...