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    • Benzenesulphonamide inhibitors of the cytolytic protein perforin 

      Spicer Julie A; Miller Christian K; O'Connor Patrick D; Jose Jiney; Huttunen Kristiina M; Jaiswal Jagdish K; Denny William A; Akhlaghi Hedieh; Browne Kylie A (Elsevier BV, 2017)
      The pore-forming protein perforin is a key component of mammalian cell-mediated immunity and essential to the pathway that allows elimination of virus-infected and transformed cells. Perforin activity has also been implicated ...