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    • Design, Synthesis and Biological Activity of Novel Substituted 3-benzoic Acid Derivatives as MtDHFR Inhibitors 

      Kronenberger, Thales; Ferreira, Glaucio Monteiro; de Souza, Alfredo Danilo Ferreira; da Silva Santos, Soraya; Poso, Antti; Ribeiro, João Augusto; Tavares, Maurício Temotheo; Pavan, Fernando Rogério; Trossini, Gustavo Henrique Goulart; Dias, Marcio Vinícius Bertacine; Parise-Filho, Roberto (Elsevier BV, 2020)
      The enzyme dihydrofolate reductase from M. tuberculosis (MtDHFR) has a high unexploited potential to be a target for new drugs against tuberculosis (TB), due to its importance for pathogen survival. Preliminary studies ...
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