Browsing by Subject "1-Oxa-9-azaspiro[5.5]undecan-4-amine"
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Discovery of Polar Spirocyclic Orally Bioavailable Urea Inhibitors of Soluble Epoxide Hydrolase
(Elsevier BV, 2018)Spirocyclic 1-oxa-9-azaspiro[5.5]undecan-4-amine scaffold was explored as a basis for the design of potential inhibitors of soluble epoxide hydrolase (sEH). Synthesis and testing of the initial SAR-probing library followed ...Tieteelliset aikakauslehtiartikkelit