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    • Synthesis and preclinical evaluation of [11C]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL) 

      Ahamed Muneer; Attili Bala; van Veghel Daisy; Ooms Maarten; Berben Philippe; Celen Sofie; Koole Michel; Declercq Lieven; Savinainen Juha R; Laitinen Jarmo T; Verbruggen Alfons; Bormans Guy (Elsevier BV, 2017)
      MAGL is a potential therapeutic target for oncological and psychiatric diseases. Our objective was to develop a PET tracer for in vivo quantification of MAGL. We report [11C]MA-PB-1 as an irreversible MAGL inhibitor PET ...