Browsing by Subject "senescence"

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    • Is metformin a geroprotector? A peek into the current clinical and experimental data 

      Zajda, Agnieszka; Huttunen, Kristiina M; Sikora, Joanna; Podsiedlik, Maria; Markowicz-Piasecka, Magdalena (, 2020)
      Nowadays we observe a growing scientific interest and need to develop novel research approach that target ageing. Metformin, apart from its proven efectiveness as a glucose-lowering agent, was found to exert multidirectional ...
      Tieteelliset aikakauslehtiartikkelit

    • MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells 

      Kuosmanen, SM; Sihvola, V; Kansanen, E; Kaikkonen, MU; Levonen, AL (Elsevier BV, 2018)
      Oxidative stress predisposes to several aging-associated diseases, such as cardiovascular diseases and cancer. In aging, increase in the production of reactive oxygen species is typically accompanied with a decline in ...
      Tieteelliset aikakauslehtiartikkelit