Browsing Artikkelit by Title
Now showing items 1-20 of 3127
-
1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) Inhibitors
(MDPI AG, 2018)We demonstrate for the first time that 4H-1,2,6-thiadiazin-4-one (TDZ) can function as a chemotype for the design of ATP-competitive kinase inhibitors. Using insights from a co-crystal structure of a 3,5-bis(arylamino)-4 ...Tieteelliset aikakauslehtiartikkelit
-
100 years of atmospheric and marine observations at the Finnish Utö Island in the Baltic Sea
(Copernicus GmbH, 2018)The Utö Atmospheric and Marine Research Station introduced in this paper is located on Utö Island (59°46.84′N, 21°22.13′E) at the outer edge of the Archipelago Sea, by the Baltic Sea towards the Baltic Proper. Meteorological ...Tieteelliset aikakauslehtiartikkelit
-
24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial
(Elsevier BV, 2017)Background Nutrition is an important modifiable risk factor in Alzheimer's disease. Previous trials of the multinutrient Fortasyn Connect showed benefits in mild Alzheimer's disease dementia. LipiDiDiet investigated the ...info:eu-repo/semantics/article
-
25 years of advances in the definition, classification and treatment of status epilepticus
(Elsevier BV, 2016)Purpose Status epilepticus (SE) requires not only urgent symptomatic treatment with antiepileptic drugs but also rapid identification and treatment of its cause. This narrative review summarizes the most important advances ...info:eu-repo/semantics/article
-
30-Day Recurrence, Readmission Rate and Clinical Outcome After Emergency Lumbar Discectomy
(Ovid Technologies (Wolters Kluwer Health), 2020)Study Design. A retrospective cohort study. Objective. To investigate the 30-day recurrence rate after emergency lumbar discectomy. Secondary aims were to investigate the factors affecting the 30-day recurrence and ...Tieteelliset aikakauslehtiartikkelit
-
3D human brain cell models: New frontiers in disease understanding and drug discovery for neurodegenerative diseases
(Elsevier BV, 2018)Neurodegenerative disorders have an enormous impact on society and healthcare budgets. There has been a high degree of failure in many recent clinical trials for disease-modifying therapeutics. A major factor in this failure ...Tieteelliset aikakauslehtiartikkelit
-
3D Morphometric analysis of calcified cartilage properties using micro-computed tomography
(Elsevier BV, 2018)Objective Our aim is to establish methods for quantifying morphometric properties of calcified cartilage (CC) from micro-computed tomography (μCT). Furthermore, we evaluated the feasibility of these methods in investigating ...Tieteelliset aikakauslehtiartikkelit
-
3D-printed, carbon-based, lossy photonic crystals: Is high electrical conductivity the must?
(Elsevier BV, 2020)The electromagnetic response of 3D-printed periodic carbon structures was investigated numerically and experimentally in the microwave (26–37 GHz) and terahertz (0.2–1.2 THz) frequency ranges. The reflection, transmission ...Tieteelliset aikakauslehtiartikkelit
-
5 years of successful inducible transgene expression following locoregional AAV delivery in nonhuman primates with no detectable immunity
(Mary Ann Liebert Inc, 2019)Anti-transgene immune responses elicited after intramuscular (i.m.) delivery of recombinant adeno-associated virus (rAAV) have been shown to hamper long-term transgene expression in large-animal models of rAAV-mediated ...Tieteelliset aikakauslehtiartikkelit
-
A 2 year physical activity and dietary intervention attenuates the increase in insulin resistance in a general population of children: the PANIC study
(Springer Science and Business Media LLC, 2020)Aims/hypothesis We studied for the first time the long-term effects of a combined physical activity and dietary intervention on insulin resistance and fasting plasma glucose in a general population of predominantly ...Tieteelliset aikakauslehtiartikkelit
-
A blockchain microsites-based ecosystem for learning and inclusion
(Brazilian Computer Society (Sociedade Brasileira de Computação - SBC), 2019)Several initiatives have made available open educational resources, offered through educational platforms, aiming to achieve a broader audience, thus having the opportunity of democratizing knowledge. However, accessibility ...Artikkelit ja abstraktit tieteellisissä konferenssijulkaisuissa
-
A Brief Survey on Six Basic and Reduced eHealth Indicators in Seven Countries in 2017
(Georg Thieme Verlag KG, 2018)Background Holistic, ubiquitous support of patient-centered health care (eHealth) at all health care institutions and in patients' homes through information processing is increasingly supplementing institution-centered ...Tieteelliset aikakauslehtiartikkelit
-
A century of trends in adult human height
(eLife Sciences Organisation, Ltd., 2016)Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height ...info:eu-repo/semantics/article
-
A cohort study on adult hematological malignancies and brain tumors in relation to magnetic fields from indoor transformer stations
(Elsevier BV, 2021)Extremely low frequency (ELF) magnetic fields (MF) have been classified as possibly carcinogenic. This classification was mainly based on studies indicating increased risk of leukemia in children living near power lines. ...Tieteelliset aikakauslehtiartikkelit
-
A Combined Field and Laboratory Study on Activated Carbon-Based Thin Layer Capping in a PCB-Contaminated Boreal Lake
(American Chemical Society (ACS), 2018)The in situ remediation of aquatic sediments with activated carbon (AC)-based thin layer capping is a promising alternative to traditional methods, such as sediment dredging. Applying a strong sorbent like AC directly to ...Tieteelliset aikakauslehtiartikkelit
-
A Comparative Re-Assessment of Feature Extractors for Deep Speaker Embeddings
(ISCA, 2020)Modern automatic speaker verification relies largely on deep neural networks (DNNs) trained on mel-frequency cepstral coefficient (MFCC) features. While there are alternative feature extraction methods based on phase, ...Artikkelit ja abstraktit tieteellisissä konferenssijulkaisuissa
-
A comparative study of magnetic chitosan (Chi@Fe3O4) and graphene oxide modified magnetic chitosan (Chi@Fe3O4GO) nanocomposites for efficient removal of Cr(VI) from water
(Elsevier BV, 2019)Magnetic chitosan (Chi@Fe3O4) nanocomposite was synthesized and modified with graphene oxide (Chi@Fe3O4GO) and the potential of both materials as adsorbents was assessed for the removal of chromium (Cr(VI)) from water. The ...Tieteelliset aikakauslehtiartikkelit
-
A comparative study on household level energy consumption and related emissions from renewable (biomass) and non-renewable energy sources in Bangladesh
(Elsevier BV, 2018)In developing countries, securing clean and equal energy access for all is often constrained by lack of understanding of households’ energy dependency and influencing factors. This study investigates household-level energy ...Tieteelliset aikakauslehtiartikkelit
-
A Comparison of Nonlinear Measures for the Detection of Cardiac Autonomic Neuropathy from Heart Rate Variability
(MDPI AG, 2015)In this work we compare three multiscale measures for their ability to discriminate between participants having cardiac autonomic neuropathy (CAN) and aged controls. CAN is a disease that involves nerve damage leading to ...info:eu-repo/semantics/article
-
A comparison of regret-based and utility-based discrete choice modelling - an empirical illustration with hospital bed choice
(Informa UK Limited, 2018)There is some concern that the unobserved preference heterogeneity in random utility maximization theory-based discrete choice experiment modelling is an important source of error variability. The randomness in utility is ...Tieteelliset aikakauslehtiartikkelit
