Browsing Luonnontieteiden, metsätieteiden ja tekniikan tiedekunta by Author "Florea, C"
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A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage
Orozco, GA; Tanska, P; Florea, C; Grodzinsky, AJ; Korhonen, RK (Springer Nature America, Inc, 2018)Cartilage provides low-friction properties and plays an essential role in diarthrodial joints. A hydrated ground substance composed mainly of proteoglycans (PGs) and a fibrillar collagen network are the main constituents ...Tieteelliset aikakauslehtiartikkelit
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Characterizing human subchondral bone properties using near-infrared (NIR) spectroscopy
Afara, IO; Florea, C; Olumegbon, IA; Eneh, CT; Malo, MKH; Korhonen, RK; Töyräs, J (Springer Nature, 2018)Degenerative joint conditions are often characterized by changes in articular cartilage and subchondral bone properties. These changes are often associated with subchondral plate thickness and trabecular bone morphology. ...Tieteelliset aikakauslehtiartikkelit
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Mechanobiological Model for Simulation of Injured Cartilage Degradation via Pro-Inflammatory Cytokines and Mechanical Stimulus
Eskelinen, ASA; Tanska, P; Florea, C; Orozco, GA; Julkunen, P; Grodzinsky, AJ; Korhonen, RK (Public Library of Science (PLoS), 2020)Post-traumatic osteoarthritis (PTOA) is associated with cartilage degradation, ultimately leading to disability and decrease of quality of life. Two key mechanisms have been suggested to occur in PTOA: tissue inflammation ...Tieteelliset aikakauslehtiartikkelit