Browsing Terveystieteiden tiedekunta by Title
Now showing items 1154-1173 of 1735
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Occupational health care personnel tackling alcohol overuse – an observational study of work processes and patient characteristics
(BioMed Central Ltd, 2022)Background Overuse of alcohol is a significant risk factor for early retirement. This observational study investigated patient characteristics and work processes in occupational health care (OHC) affecting practices in ...
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Occupational health care return-to-work practices for workers with job burnout
(Informa UK Limited, 2019)Background: Occupational health care supports return to work in cases of burnout; however, there is little research on return-to-work practices. Aim: To describe occupational health care return-to-work practices for ...Tieteelliset aikakauslehtiartikkelit
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Occupational Well-Being: A Structural Equation Model of Finnish and Estonian School
(Canadian Center of Science and Education, 2018)This study aimed to test the original Occupational Well-being of School Staff Model (OWSS Model) from 2005. This model was tested using data collected in two stages (in 2010 and in 2013) from school staff in Finnish and ...Tieteelliset aikakauslehtiartikkelit
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Occurrence and Classification of Cerebrovascular Events after Isolated Bioprosthetic Surgical Aortic Valve Replacement: A Competing Risk Analysis of the CAREAVR Study
(Informa UK Limited, 2018)Background: The long-term incidence of stroke and the proportion of cardioembolic events after bioprosthetic surgical aortic valve replacement (SAVR) remain largely unknown. Methods: The CAREAVR study sought to assess ...Tieteelliset aikakauslehtiartikkelit
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Ocular Intracameral Pharmacokinetics for a Cocktail of Timolol, Betaxolol, and Atenolol in Rabbits
(American Chemical Society (ACS), 2019)The mechanisms of drug clearance from the aqueous humor are poorly defined. In this study, a cocktail approach was used to simultaneously determine the pharmacokinetics of three β-blocker agents after intracameral (ic) ...Tieteelliset aikakauslehtiartikkelit
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Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations
(Elsevier, 2022)Quantitation of ocular drug metabolism is important, but only sparse data is currently available. Herein, the pharmacokinetics of four drugs, substrates of metabolizing enzymes, was investigated in albino rabbit eyes after ...
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Ocular Phenotype of Mice with Impaired Fibrillin-1 Function on Hypercholesterolemic Apolipoprotein E-Deficient Background
(Gratis Open Access Publishers LLC, 2018)Aim: Transgenic mice with an elastic fiber mutation (C1039G+/-) in the fibrillin-1 gene and apolipoprotein E deficiency express vulnerable atherosclerotic plaque formation in the aorta and coronary and carotid arteries. ...Tieteelliset aikakauslehtiartikkelit
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Olfactory cell cultures to investigate health effects of air pollution exposure: implications for neurodegeneration
(Elsevier BV, 2020)Air pollution is a major, global public health concern. A growing body of evidence shows that exposure to air pollutants may impair the brain. Living in highly polluted areas has been linked to several neurodegenerative ...Tieteelliset aikakauslehtiartikkelit
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Olkapään degeneratiivisen kiertäjäkalvosinrepeämän hoito
(Suomen ortopediayhdistys ry, 2017)info:eu-repo/semantics/article
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Omiikka työkaluksi leukemian hoitojen suunnitteluun
(Suomalainen lääkäriseura Duodecim, 2021)Kansallisia hankkeita genomitiedon tuomiseksi syöpädiagnostiikkaan on käynnissä useassa Euroopan maassa. Sekvensointiteknologian avulla voidaan samanaikaisesti tunnistaa yhden emäsparin mutaatioita, laajempia DNA:n lisäyksiä ...Tieteelliset aikakauslehtiartikkelit
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Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma
(Landes Bioscience; European Academy of Tumor Immunology, 2016)The stimulation of the immune system using oncolytic adenoviruses (OAds) has attracted significant interest and several studies suggested that OAds immunogenicity might be important for their efficacy. Therefore, we developed ...info:eu-repo/semantics/article
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Onko olkapään kiertäjäkalvosimen repeämän hoitopaikka kuntosali vai leikkaussali?
(Suomen lääkäriliitto, 2022)Olkapään kiertäjäkalvosimen repeämä voi syntyä jänteen rappeuman, äkillisen tapaturman tai näiden yhdistelmän seurauksena. Suurin osa on oireettomia eikä tarvitse hoitoa. Tyypillisiä oireita ovat levossa tai rasituksessa ...
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Operative versus non-operative treatment for 2-part proximal humerus fracture: A multicenter randomized controlled trial
(Public Library of Science, 2019)Background Although increasingly used, the benefit of surgical treatment of displaced 2-part proximal humerus fractures has not been proven. This trial evaluates the clinical effectiveness of surgery with locking plate ...article
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Opinions on conscientious objection to induced abortion among Finnish medical and nursing students and professionals
(BioMed Central, 2015)Background: Conscientious objection (CO) to participating in induced abortion is not present in the Finnish health care system or legislation unlike in many other European countries. Methods: We conducted a questionnaire ...info:eu-repo/semantics/article
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Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease
(Springer Science and Business Media LLC, 2019)Background Hip fractures are common among persons with Alzheimer’s disease (AD), but problems in pain assessment may lead to insufficient analgesia after hospitalization. Objective We investigated the prevalence of ...Tieteelliset aikakauslehtiartikkelit
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Opioids and Falls Risk in Older Adults: A Narrative Review
(Springer Nature, 2022)Pain treatment is important in older adults but may result in adverse events such as falls. Opioids are effective for nociceptive pain but the evidence for neuropathic pain is weak. Nevertheless, both pain and opioids may ...
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Optics-based compressibility parameter for pharmaceutical tablets obtained with the aid of the terahertz refractive index
(Elsevier BV, 2017)The objective of this study is to propose a novel optical compressibility parameter for porous pharmaceutical tablets. This parameter is defined with the aid of the effective refractive index of a tablet that is obtained ...info:eu-repo/semantics/article
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Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)
(Springer Nature, 2018)Background Based on epidemiological and clinical data acute appendicitis can present either as uncomplicated (70–80%) or complicated (20–30%) disease. Recent studies have shown that antibiotic therapy is both safe and ...Tieteelliset aikakauslehtiartikkelit
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Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor
(Springer Nature, 2018)Lentiviral vectors (LVs) are promising tools for gene therapy. However, scaling up the production methods of LVs in order to produce high-quality vectors for clinical purposes has proven to be difficult. In this article, ...info:eu-repo/semantics/article
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Optimized Protocol for Accurate Titration of Adeno-Associated Virus Vectors
(Mary Ann Liebert Inc, 2021)Adeno-associated virus (AAV) is currently the most popular gene delivery vector for in vivo gene therapy. However, variability in titration methods between different laboratories affects the reproducibility of experiments ...Tieteelliset aikakauslehtiartikkelit