Browsing Terveystieteiden tiedekunta by Title

Now showing items 427-446 of 1735

    • Development and implementation of a geographical area categorisation method with targeted performance indicators for nationwide EMS in Finland 

      Pappinen J; Laukkanen-Nevala P; Mäntyselkä P; Kurola J. (Springer Nature, 2018)
      Background In Finland, hospital districts (HD) are required by law to determine the level and availability of Emergency Medical Services (EMS) for each 1-km2 sized area (cell) within their administrative area. The cells ...
      Tieteelliset aikakauslehtiartikkelit

    • Development and Psychometric Testing of the Registered Nurses' Perceptions of Rewarding Scale 

      Seitovirta, Jaana; Lehtimäki, Aku-Ville; Vehviläinen-Julkunen, Katri; Mitronen, Lasse; Kvist, Tarja (Ovid Technologies (Wolters Kluwer Health), 2018)
      Background: Rewarding is a powerful way to recognize, manage, and retain staff. However, the perceptions of registered nurses (RNs) toward rewarding have not yet been extensively examined in nursing studies. It is important ...
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    • Development and testing of an instrument (HeSoEduCo) for health and social care educators' competence in professional education 

      Mikkonen, Kristina; Tuomikoski, Anna-Maria; Sjögren, Tuulikki; Koivula, Meeri; Koskimäki, Minna; Lähteenmäki, Marja-Leena; Mäki-Hakola, Hanne; Wallin, Outi; Sormunen, Marjorita; Saaranen, Terhi; Koskinen, Camilla; Koskinen, Monika; Salminen, Leena; Holopainen, Arja; Kääriäinen, Maria (Elsevier BV, 2020)
      Background Health and social care education is highly important for preparing future professionals for their future roles in sustainable health and social care. However, previous studies have emphasized that health and ...
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    • Development of a fermented quinoa-based beverage 

      Ludena Urquizo Fanny Emma; García Torres Silvia Melissa; Tolonen Tiina; Jaakkola Mari; Grazzia Pena-Niebuhr Maria; von Wright Atte; Repo-Carrasco-Valencia Ritva; Korhonen Hannu; Plumed-Ferrer Carme (Wiley-Blackwell, 2016)
      Quinoa is a crop that originated from the Andes. It has high nutritional value, outstanding agro-ecological adaptability, and low water requirements. Quinoa is an excellent crop alternative to help overcome food shortages, ...
      info:eu-repo/semantics/article

    • Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure 

      Konings, GF; Saarinen, N; Delvoux, B; Kooreman, L; Koskimies, P; Krakstad, C; Fasmer, KE; Haldorsen, IS; Zaffagnini, A; Häkkinen, MR; Auriola, S; Dubois, L; Lieuwes, N; Verhaegen, F; Schyns, LE; Kruitwagen, RF; Xanthoulea, S; Romano, A (MDPI AG, 2018)
      Endometrial cancer (EC) is the most common gynaecological malignancy in Western society and the majority of cases are estrogen dependent. While endocrine drugs proved to be of insufficient therapeutic value in the past, ...
      Tieteelliset aikakauslehtiartikkelit

    • Development of an International Tool for Students to Record and Reflect on Patient Safety Learning Experiences 

      Steven, Alison; Pearson, Pauline; Turunen, Hannele; Myhre, Kristin; Sasso, Loredana; Vizcaya-Moreno, Maria Flores; Pérez-Cañaveras, Rosa María; Sara-Aho, Arja; Bagnasco, Annamaria; Aleo, Giuseppe; Patterson, Lucy; Larkin, Valerie; Zanini, Milko; Porras, Jari; Khakurel, Jayden; Azimirad, Mina; Ringstad, Øystein; Johnsen, Lasse; Haatainen, Kaisa; Wilson, Gemma; Rossi, Silvia; Morey, Sarah; Tella, Susanna (Ovid Technologies (Wolters Kluwer Health), 2021)
      Background: Underpinning all nursing education is the development of safe practitioners who provide quality care. Learning in practice settings is important, but student experiences vary. Purpose: This study aimed ...
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    • Development of corticospinal motor excitability and cortical silent period from mid-childhood to adulthood - a navigated TMS study 

      Säisänen, Laura; Julkunen, Petro; Lakka, Timo; Lindi, Virpi; Könönen, Mervi; Määttä; Sara (Elsevier BV, 2018)
      Objectives We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childhood to adulthood using electric field (EF) navigated TMS and correlated the results with manual ...
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    • Development of New Coumarin-Based Profluorescent Substrates for Human Cytochrome P450 Enzymes 

      Juvonen, Risto O; Ahinko, Mira; Huuskonen, Juhani; Raunio, Hannu; Pentikäinen, Olli T (2018)
      1. Cytochrome P450 (CYP) enzymes constitute an essential xenobiotic metabolizing system that regulates the elimination of lipophilic compounds from the body. Convenient and affordable assays for CYP enzymes are important ...
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    • Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining 

      Haidar Samer; Bouaziz Zouhair; Marminon Christelle; Laitinen Tuomo; Poso Antti; Le Borgne Marc; Jose Joachim (MDPI AG, 2017)
      Protein kinase CK2, initially designated as casein kinase 2, is an ubiquitously expressed serine/threonine kinase. This enzyme, implicated in many cellular processes, is highly expressed and active in many tumor cells. A ...
      info:eu-repo/semantics/article

    • DHCR24 exerts neuroprotection upon inflammation-induced neuronal death 

      Martiskainen H; Paldanius KMA; Natunen T; Takalo M; Marttinen M; Leskelä S; Huber N; Mäkinen P; Bertling E; Dhungana H; Huuskonen M; Honkakoski P; Hotulainen P; Rilla K; Koistinaho J; Soininen H; Malm T; Haapasalo A; Hiltunen M (Springer Nature, 2017)
      Background DHCR24, involved in the de novo synthesis of cholesterol and protection of neuronal cells against different stress conditions, has been shown to be selectively downregulated in neurons of the affected brain ...
      info:eu-repo/semantics/article

    • Diabetes and impaired glucose metabolism is associated with more cold-related cardiorespiratory symptoms 

      Ikäheimo TM; Jokelainen J; Hassi J; Hiltunen L; Keinänen-Kiukaanniemi S; Laatikainen T; Jousilahti P; Peltonen M; Moilanen L; Saltevo J; Näyhä S (Elsevier BV, 2017)
      Aims Diabetes and impaired glucose metabolism cause metabolic, neural and circulatory disturbances that may predispose to adverse cooling and related symptoms during the cold season. This study assessed the prevalence of ...
      info:eu-repo/semantics/article

    • Diabetes hospitalizations and deaths in a cohort of treatment-seeking illicit drug users 

      Aregbesola, Alex; Onyeka, Ifeoma N; Olubamwo, Olubunmi; Ronkainen, Kimmo; Tiihonen, Jari; Föhr, Jaana; Kauhanen, Jussi (SAGE Publications, 2018)
      Background: Studies on diabetes among illicit drug users are scarce in Finland. This study aimed to describe hospitalization and death due to diabetes among treatment-seeking illicit drug users. Methods: Information ...
      Tieteelliset aikakauslehtiartikkelit

    • Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver 

      García-Calzón Sonia; Perfilyev Alexander; Männistö Ville; de Mello Vanessa D; Nilsson Emma; Pihlajamäki Jussi; Ling Charlotte (Springer Nature, 2017)
      Background Given that metformin is the most common pharmacological therapy for type 2 diabetes, understanding the function of this drug is of great importance. Hepatic metformin transporters are responsible for the ...
      info:eu-repo/semantics/article

    • Diagnosis of Knee Osteochondral Lesions With Ultrasound 

      Penttilä, Pekko; Liukkonen, Jukka; Joukainen, Antti; Virén, Tuomas; Jurvelin, Jukka S; Töyräs, Juha; Kröger, Heikki (Elsevier BV, 2015)
      Evaluation of articular cartilage and subchondral bone is essential in the diagnosis of joint diseases and injuries. Interobserver and intraobserver reproducibilities of arthroscopic grading are only poor to moderate. Thus, ...
      info:eu-repo/semantics/article

    • Dialektinen käyttäytymisterapia on tehokas ja käytännönläheinen hoitomenetelmä tunne-elämän epävakauteen liittyvän itsetuhoisuuden vähentämisessä 

      Kekkonen, Virve; Koivisto, Maaria; Lindeman, Sari; Tolmunen, Tommi (Suomalainen lääkäriseura Duodecim, 2022)
      Itsetuhoisuudesta muodostuu joskus ainoa selviytymiskeino tunne-elämän epävakaudesta johtuviin kestämättömiin tunnetiloihin. Dialektisen käyttäytymisterapian (DKT) tavoitteena on itsetuhoisen käyttäytymisen väheneminen ...

    • Dietary fatty acids were not independently associated with lipoprotein subclasses in elderly women 

      Alaghehband FR; Lankinen M; Värri M; Sirola J; Kröger H; Erkkilä AT (Elsevier BV, 2017)
      Dietary fatty acids are known to affect serum lipoproteins; however, little is known about the associations between consumption of dietary fatty acids and lipoprotein subclasses. In this study, we hypothesized that there ...
      info:eu-repo/semantics/article

    • Dietary fiber from oat and rye brans ameliorate Western diet-induced body weight gain and hepatic inflammation by the modulation of short chain fatty acids, bile acids, and tryptophan metabolism 

      Kundi, Zuzanna Maria; Lee, Jetty Chung-Yung; Pihlajamäki, Jussi; Chan, Chi Bun; Leung, Kin Sum; So, Stephanie Sik Yu; Nordlund, Emilia; Kolehmainen, Marjukka; El-Nezami, Hani (Wiley, 2021)
      Scope Dietary fiber (DF) induces changes in gut microbiota function and thus modulates the gut environment. How this modulation is associated with metabolic pathways related to the gut is largely unclear. This study aims ...
      Tieteelliset aikakauslehtiartikkelit

    • Dietary intake of magnesium and the risk of epilepsy in middle-aged and older Finnish men : a 22-year follow-up study in general population 

      Yary, Teymoor; Kauhanen, Jussi (Elsevier BV, 2019)
      Objectives Magnesium may play an important role in the prevention or treatment of epilepsy. We aimed to examine the association between dietary intake of magnesium and the incidence of epilepsy in middle-aged Finnish men ...
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    • Dietary n-3 PUFA augments pre-ovulatory follicle turnover and prolificacy in well-fed ewes 

      Mahla, Ajit Singh; Bunkar, Suresh Kumar; Kumawat, Babu Lal; Kumar Saxena, Vijay; Selvaraju, Sellappan; Bhatt, Randhir Singh; Singh, Raghvendar; Kumar, Arun (Elsevier B.V, 2023)
      The present study evaluated the effect of dietary supplementation with n-3 polyunsaturated fatty acids (PUFA) on preovulatory follicle (POF) turnover, prolificacy, and endocrine and metabolic milieu in Malpura sheep. Fifty ...

    • Difference in Rupture Risk Between Familial and Sporadic Intracranial Aneurysms: An Individual Patient Data Meta-analysis 

      Zuurbier, Charlotte CM; Mensing, Liselore A; Wermer, Marieke JH; Juvela, Seppo; Lindgren, Antti E; Koivisto, Timo; Jääskeläinen, Juha E; Yamazaki, Tomosato; Molenberg, Rob; Dijk, J Marc C van; Uyttenboogaart, Maarten; Aalbers, Marlien; Morita, Akio; Tominari, Shinjiro; Arai, Hajime; Nozaki, Kazuhiko; Murayama, Yuichi; Ishibashi, Toshihiro; Takao, Hiroyuki; Rinkel, Gabriel JE et al (Ovid Technologies (Wolters Kluwer Health), 2021)
      Background and Objectives We combined individual patient data (IPD) from prospective cohorts of patients with unruptured intracranial aneurysms (UIAs) to assess to what extent patients with familial UIA have a higher rupture ...
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