Now showing items 542-561 of 1735

    • Endocrine effects of sauna bath 

      Huhtaniemi, IT; Laukkanen, JA (Elsevier BV, 2020)
      Sauna bath brings about numerous acute changes in hormone levels, partly akin to other stressful situations, partly specific for sauna. Norepinephrine increases in those accustomed to sauna bath. Sweating increases the ...
      Tieteelliset aikakauslehtiartikkelit

    • Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics 

      Kärkkäinen, Olli K; Lehtonen, Marko; Laukkanen, Virpi; Tupala, Erkki; Hyytiä, Petri; Kautiainen, Hannu; Tiihonen, Jari; Callaway, JC; Storvik, Markus (Elsevier BV, 2013)
      Accumulating evidence continues to link certain aspects of the endogenous cannabinoid (EC) system with alcohol dependence, negative-reinforcement learning, and the modulation of stress responses. Specific alterations in ...
      article

    • Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions 

      Niskanen H; Tuszynska I; Zaborowski R; Heinäniemi M; Ylä-Herttuala S; Wilczynski B; Kaikkonen MU (Oxford University Press (OUP), 2018)
      Endothelial cells (ECs) differentiate from mesodermal progenitors during vasculogenesis. By comparing changes in chromatin interactions between human umbilical vein ECs, embryonic stem cells and mesendoderm cells, we ...
      info:eu-repo/semantics/article

    • Engaging older people in an internet platform for cardiovascular risk self-management: a qualitative study among Dutch HATICE participants 

      van Middelaar, T; Beishuizen, CRL; Guillemont, J; Barbera, M; Richard, E; Moll, van Charante EP on behalf of the HATICE consortium (BMJ, 2018)
      Objectives To study older peoples’ experiences with an interactive internet platform for cardiovascular self-management, to assess which factors influence initial and sustained engagement. To assess their views on future ...
      Tieteelliset aikakauslehtiartikkelit

    • Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes 

      Aittola, Kirsikka; Karhunen, Leila; Männikkö, Reija; Järvelä-Reijonen, Elina; Mikkonen, Santtu; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Harjumaa, Marja; Lindström, Jaana; Lakka, Timo; Tilles-Tirkkonen, Tanja; Pihlajamäki, Jussi (MDPI AG, 2021)
      Eating competence (EC) is characterized by positive attitudes towards food and eating, having regular meals, eating a variety of foods, and internally regulated eating. We investigated the associations of changes in EC ...
      Tieteelliset aikakauslehtiartikkelit

    • Enhanced gene expression by a novel designed leucine zipper endosomolytic peptide 

      Ahmad, Aqeel; Rilla, Kirsi; Zou, Jing; Zhang, Weikai; Pyykkö, Ilmari; Kinnunen, Paavo; Ranjan, Sanjeev (Elsevier BV, 2021)
      An endosomal trap is a major barrier in gene therapy. We have designed an endosomolytic peptide based on the leucine zipper sequence and characterized it both structurally and functionally. The results illustrated that ...
      Tieteelliset aikakauslehtiartikkelit

    • Ennenaikainen adrenarke: yleinen, moni-ilmeinen ja hyväennusteinen kehitysvariantti 

      Liimatta, Jani; Utriainen, Pauliina; Voutilainen, Raimo; Jääskeläinen, Jarmo (Suomalainen lääkäriseura Duodecim, 2020)
      Adrenarke eli lisämunuaiskuoren kypsymisen aiheuttama "androgeeninen murrosikä" kuuluu lapsuuden normaaliin fysiologiseen kehitykseen, mutta sen perimmäistä merkitystä ei tunneta. Ennenaikainen adrenarke on liitetty ...
      Tieteelliset aikakauslehtiartikkelit

    • Enthusiastic Academic and Support Service Staff as an Agent for Change: A Case Study Based on a Project in African Higher Education Institutes 

      Haaranen, Ari; Saarti, Jarmo (Academic Conferences and Publishing International - ACPIL, 2020)
      The aim of this case study was to evaluate whether there had been educational changes and if so, in which phases of implementation and institutionalization in three African higher education institutions. The changes were ...
      Tieteelliset aikakauslehtiartikkelit

    • Environmental Correlates of Motor Competence in Children - The Skilled Kids Study 

      Niemistö, D; Finni, T; Haapala, EA; Cantell, M; Korhonen, E; Sääkslahti, A (MDPI AG, 2019)
      Environment, physical activity (PA) and motor development are tightly interwoven during childhood. We examined the associations of environmental factors with motor competence (MC) in children. Children (N = 945, 50.1% boys, ...
      Tieteelliset aikakauslehtiartikkelit

    • Environmental Intolerance, Symptoms and Disability Among Fertile-Aged Women 

      Vuokko, Aki; Karvala, Kirsi; Lampi, Jussi; Keski-Nisula, Leea; Pasanen, Markku; Voutilainen, Raimo; Pekkanen, Juha; Sainio, Markku (MDPI AG, 2018)
      The purpose was to study the prevalence of environmental intolerance (EI) and its different manifestations, including behavioral changes and disability. Fertile-aged women (n = 680) of the Kuopio Birth Cohort Study were ...
      Tieteelliset aikakauslehtiartikkelit

    • Environmental responsibility in hospital care: Findings from a qualitative study 

      Kallio, Hanna; Pietilä, Anna-Maija; Johnson, Martin; Kangasniemi, Mari (Sciedu Press, 2018)
      Objective: To identify the key elements of environmental responsibility in hospital care and the stakeholders involved. Background: Hospital care causes a significant global environmental burden, which threatens human ...
      Tieteelliset aikakauslehtiartikkelit

    • Environmental responsibility in nursing in hospitals: A modified Delphi study of nurses' views 

      Kallio, Hanna; Pietilä, Anna-Maija; Kangasniemi, Mari (Wiley, 2020)
      Objectives To identify nurses' views on environmentally responsible clinical practices, and to examine their consensus regarding the stakeholders and their roles and tools needed to promote, and enable, environmental ...
      Tieteelliset aikakauslehtiartikkelit

    • Epäsuorat altistuskokeet astman diagnosoinnissa 

      Koskela, Heikki; Tikkakoski, Antti; Karjalainen, Jussi; Mäkelä, Mika; Malmberg, Pekka (Suomalainen lääkäriseura Duodecim, 2019)
      Keuhkoputkien supistusherkkyyttä voidaan mitata epäsuorilla altistuskokeilla, mikäli astman perustutkimukset eivät varmista taudin määritystä. Astmadiagnoosiin tähtäävässä rasituskokeessa kannattaa käyttää juoksurasitusta, ...
      Tieteelliset aikakauslehtiartikkelit

    • Epävakaaseen persoonallisuuteen liittyvän psykologisen kivun ymmärtämisestä ja kohtaamisesta 

      Koivisto, Maaria; Lindeman, Sari M (Suomalainen lääkäriseura Duodecim, 2023)
      Psykologinen kipu on subjektiivinen, usein kestämättömänä koettu mielentila, jota luonnehtivat kielteinen minäkuva sekä kokemus keinottomuudesta, psykologisten tarpeiden kohtaamatta jäämisestä ja sosiaalisen yhteyden ...

    • EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF 

      Groppa, E; Brkic, S; Uccelli, A; Wirth, G; Korpisalo-Pirinen, P; Filippova, M; Dasen. B; Sacchi, V; Muraro, MG; Trani, M; Reginato, S; Gianni-Barrera, R; Ylä-Herttuala, S; Banfi A (EMBO, 2018)
      Vascular endothelial growth factor (VEGF) is the master regulator of angiogenesis, whose best‐understood mechanism is sprouting. However, therapeutic VEGF delivery to ischemic muscle induces angiogenesis by the alternative ...
      Tieteelliset aikakauslehtiartikkelit

    • Epidemiology of Kawasaki disease before and after universal Bacille Calmette-Guérin vaccinations were discontinued 

      Pasma, Hanna; Honkila, Minna; Pokka, Tytti; Renko, Marjo; Salo, Eeva; Tapiainen, Terhi (Wiley, 2020)
      Aim Bacille Calmette‐Guérin (BCG) vaccine (BCG) has been suggested to induce the primary immunity needed for the subsequent Kawasaki disease (KD). We studied the epidemiology of KD before and after the universal BCG ...
      Tieteelliset aikakauslehtiartikkelit

    • Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study 

      Cardona, A; Day, FR; Perry, JRB; Loh, M; Chu, AY; Lehne, B; Paul, DS; Lotta, LA; Stewart, ID; Kerrison, ND; Scott, RA; Khaw, KT; Forouhi, NG; Langenberg, C; Liu, C; Mendelson, MM; Levy, D; Beck, S; Leslie, RD; Dupuis, J; et al. incl. Pihlajamäki, J (American Diabetes Association, 2019)
      Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, ...
      Tieteelliset aikakauslehtiartikkelit

    • Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF 

      Seuter, Sabine; Neme, Antonio; Carlberg, Carsten (Oxford University Press on behalf of Nucleic Acids Research., 2015)
      The physiological functions of vitamin D are mediated by its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) activating the transcription factor vitamin D receptor (VDR). In THP-1 human monocytes we demonstrated ...
      info:eu-repo/semantics/article

    • Epilepsy biomarkers - Toward etiology and pathology specificity 

      Pitkänen, Asla; Ekolle, Ndode-Ekane Xavier; Lapinlampi, Niina; Puhakka, Noora (Elsevier BV, 2019)
      A biomarker is a characteristic that is measured as an indicator of normal biologic processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities ...
      Tieteelliset aikakauslehtiartikkelit

    • Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage 

      Huttunen J; Lindgren A; Kurki MI; Huttunen T; Frösen J; Koivisto T; von und zu Fraunberg M; Immonen A; Jääskeläinen JE; Kälviäinen R (Ovid Technologies (Wolters Kluwer Health), 2017)
      Objective: To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors of subarachnoid hemorrhage from saccular intracranial aneurysm (SIA-SAH). Methods: The ...
      info:eu-repo/semantics/article