Now showing items 552-571 of 1735

    • Environmental responsibility in hospital care: Findings from a qualitative study 

      Kallio, Hanna; Pietilä, Anna-Maija; Johnson, Martin; Kangasniemi, Mari (Sciedu Press, 2018)
      Objective: To identify the key elements of environmental responsibility in hospital care and the stakeholders involved. Background: Hospital care causes a significant global environmental burden, which threatens human ...
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    • Environmental responsibility in nursing in hospitals: A modified Delphi study of nurses' views 

      Kallio, Hanna; Pietilä, Anna-Maija; Kangasniemi, Mari (Wiley, 2020)
      Objectives To identify nurses' views on environmentally responsible clinical practices, and to examine their consensus regarding the stakeholders and their roles and tools needed to promote, and enable, environmental ...
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    • Epäsuorat altistuskokeet astman diagnosoinnissa 

      Koskela, Heikki; Tikkakoski, Antti; Karjalainen, Jussi; Mäkelä, Mika; Malmberg, Pekka (Suomalainen lääkäriseura Duodecim, 2019)
      Keuhkoputkien supistusherkkyyttä voidaan mitata epäsuorilla altistuskokeilla, mikäli astman perustutkimukset eivät varmista taudin määritystä. Astmadiagnoosiin tähtäävässä rasituskokeessa kannattaa käyttää juoksurasitusta, ...
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    • Epävakaaseen persoonallisuuteen liittyvän psykologisen kivun ymmärtämisestä ja kohtaamisesta 

      Koivisto, Maaria; Lindeman, Sari M (Suomalainen lääkäriseura Duodecim, 2023)
      Psykologinen kipu on subjektiivinen, usein kestämättömänä koettu mielentila, jota luonnehtivat kielteinen minäkuva sekä kokemus keinottomuudesta, psykologisten tarpeiden kohtaamatta jäämisestä ja sosiaalisen yhteyden ...

    • EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF 

      Groppa, E; Brkic, S; Uccelli, A; Wirth, G; Korpisalo-Pirinen, P; Filippova, M; Dasen. B; Sacchi, V; Muraro, MG; Trani, M; Reginato, S; Gianni-Barrera, R; Ylä-Herttuala, S; Banfi A (EMBO, 2018)
      Vascular endothelial growth factor (VEGF) is the master regulator of angiogenesis, whose best‐understood mechanism is sprouting. However, therapeutic VEGF delivery to ischemic muscle induces angiogenesis by the alternative ...
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    • Epidemiology of Kawasaki disease before and after universal Bacille Calmette-Guérin vaccinations were discontinued 

      Pasma, Hanna; Honkila, Minna; Pokka, Tytti; Renko, Marjo; Salo, Eeva; Tapiainen, Terhi (Wiley, 2020)
      Aim Bacille Calmette‐Guérin (BCG) vaccine (BCG) has been suggested to induce the primary immunity needed for the subsequent Kawasaki disease (KD). We studied the epidemiology of KD before and after the universal BCG ...
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    • Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study 

      Cardona, A; Day, FR; Perry, JRB; Loh, M; Chu, AY; Lehne, B; Paul, DS; Lotta, LA; Stewart, ID; Kerrison, ND; Scott, RA; Khaw, KT; Forouhi, NG; Langenberg, C; Liu, C; Mendelson, MM; Levy, D; Beck, S; Leslie, RD; Dupuis, J; et al. incl. Pihlajamäki, J (American Diabetes Association, 2019)
      Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, ...
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    • Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF 

      Seuter, Sabine; Neme, Antonio; Carlberg, Carsten (Oxford University Press on behalf of Nucleic Acids Research., 2015)
      The physiological functions of vitamin D are mediated by its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) activating the transcription factor vitamin D receptor (VDR). In THP-1 human monocytes we demonstrated ...
      info:eu-repo/semantics/article

    • Epilepsy biomarkers - Toward etiology and pathology specificity 

      Pitkänen, Asla; Ekolle, Ndode-Ekane Xavier; Lapinlampi, Niina; Puhakka, Noora (Elsevier BV, 2019)
      A biomarker is a characteristic that is measured as an indicator of normal biologic processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities ...
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    • Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage 

      Huttunen J; Lindgren A; Kurki MI; Huttunen T; Frösen J; Koivisto T; von und zu Fraunberg M; Immonen A; Jääskeläinen JE; Kälviäinen R (Ovid Technologies (Wolters Kluwer Health), 2017)
      Objective: To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors of subarachnoid hemorrhage from saccular intracranial aneurysm (SIA-SAH). Methods: The ...
      info:eu-repo/semantics/article

    • Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies 

      Pennells, L; Kaptoge, S; Wood, A; Sweeting, M; Zhao, X; White, I; Burgess, S; Willeit, P; Bolton, T; Moons, KGM; van der Schouw, YT; Selmer, R; Khaw, KT; Gudnason, V; Assmann, G; Amouyel, P; Salomaa, V; Kivimaki, M; Nordestgaard, BG; Blaha, MJ; et al (Oxford University Press (OUP), 2018)
      Aims There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after ...
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    • ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease 

      Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu (Springer Science and Business Media LLC, 2020)
      The endoplasmic reticulum (ER) contains stress sensors which recognize the accumulation of unfolded proteins within the lumen of ER, and subsequently these transducers stimulate the unfolded protein response (UPR). The ER ...
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    • Eristys päivähoidosta infektion vuoksi 

      Peltola, Ville; Renko, Marjo (Suomalainen lääkäriseura Duodecim, 2021)
      Pienet lapset sairastavat paljon tarttuvia tauteja, ja päiväkodissa kontaktit ovat tiiviitä. Lapsen poissaolo päivähoidosta määräytyy ennen kaikkea hänen vointinsa mukaan: sairas lapsi hoidetaan kotona, ja hoitoon voi ...
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    • ERN-verkostot kokoavat harvinaissairauksien osaajat yhteen 

      Lempainen, Johanna; Kälviäinen, Reetta; Heiskanen-Kosma, Tarja (Suomen lääkäriliitto, 2023)
      • EU:n alaisuuteen on vuodesta 2017 alkaen perustettu yhteensä 24 harvinaissairauksien ERN-osaamisverkostoa. Kaikissa on vähintään yksi suomalainen jäsenkeskus. • Verkostot auttavat tavoittamaan asiantuntijoita koko EU:ssa. ...

    • ESGCT 2017 in Berlin: Clear Steps Forward 

      Ylä-Herttuala S (Elsevier BV, 2017)
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    • Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling 

      Zhou, Zhenqi; Moore, Timothy M; Drew, Brian G; Ribas, Vicent; Wanagat, Jonathan; Civelek, Mete; Segawa, Mayuko; Wolf, Dane M; Norheim, Frode; Seldin, Marcus M; Strumwasser, Alexander R; Whitney, Kate A; Lester, Ellen; Reddish, Britany R; Vergnes, Laurent; Reue, Karen; Rajbhandari, Prashant; Tontonoz, Peter; Lee, Jason; Mahata, Sushil K [et al incl. Laakso, Markku] (American Association for the Advancement of Science (AAAS), 2020)
      Obesity is heightened during aging, and although the estrogen receptor α (ERα) has been implicated in the prevention of obesity, its molecular actions in adipocytes remain inadequately understood. Here, we show that adipose ...
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    • Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation 

      Abubakar, M; Chang-Claude, J; Ali, HR; Chatterjee, N; Coulson, P; Daley, F; Blows, F; Benitez, J; Milne, RL; Brenner, H; Stegmaier, C; Mannermaa, A; Rudolph, A; Sinn, P; Couch, FJ; Devilee, P; Tollenaar, RA; Seynaeve, C; Figueroa, J; Lissowska, J; et al. (Wiley, 2018)
      Limited epidemiological evidence suggests that the etiology of hormone receptor positive (HR+) breast cancer may differ by levels of histologic grade and proliferation. We pooled risk factor and pathology data on 5,905 HR+ ...
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    • Etiology, syndrome diagnosis, and cognition in childhood-onset epilepsy: A population-based study 

      Sokka Arja; Olsen Päivi; Kirjavainen Jarkko; Harju Maijakaisa; Keski-Nisula Leea; Räisänen Sari; Heinonen Seppo; Kälviäinen Reetta (Wiley-Blackwell, 2017)
      Objective To evaluate the prevalence of various etiologies of epilepsies and epilepsy syndromes and to estimate cognitive function in cases of childhood-onset epilepsy. Methods A population-based retrospective registry ...
      info:eu-repo/semantics/article

    • European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) 

      Egea J; Fabregat I; Frapart YM; Ghezzi P; Görlach A; Kietzmann T; Kubaichuk K; Knaus UG; Lopez MG; Olaso-Gonzalez G; Petry A; Schulz R1; Vina J; Winyard P; Abbas K; Ademowo OS; Afonso CB; Andreadou I; Antelmann H; Antunes F; Aslan M; Bachschmid MM; Barbosa RM; Belousov V; Berndt C; Bernlohr D; Bertrán E; Bindoli A; Bottari SP; Brito PM; Carrara G; Casas AI; Chatzi A; Chondrogianni N; Conrad M; Cooke MS; Costa JG; Cuadrado A; My-Chan Dang P; De Smet B; Debelec-Butuner B; Dias IHK; Dunn JD; Edson AJ; Giniatullin R; et al (Elsevier BV, 2017)
      The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different ...
      info:eu-repo/semantics/article

    • European health examination surveys - a tool for collecting objective information about the health of the population 

      Tolonen, Hanna; Koponen, Päivikki; Al-kerwi, Ala'a; Capkova, Nada; Giampaoli, Simona; Mindell, Jennifer; Paalanen, Laura; Ruiz-Castell, Maria; Trichopoulou, Antonia; Kuulasmaa, Kari; the EHES Network incl. Diem, Günter; van der Heyden, Johan; Dimitrov, Plamen; Lappée, Marcel; Kubinova, Ruzena; Jørgensen, Torben; Linneberg, Allan; Grønbæk, Morten; Eriksen, Louise; Laatikainen, Tiina (Springer Nature, 2018)
      Background Representative and reliable data on health and health determinants of the population and population sub-groups are needed for evidence-informed policy making; planning and evaluation of prevention programmes; ...
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