Browsing Terveystieteiden tiedekunta by Title
Now showing items 722-741 of 1735
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Heart rate variability and occupational stress - systematic review
(National Institute of Industrial Health, 2018)The aim of this systematic review was to explore studies regarding association between occupational stress and heart rate variability (HRV) during work. We searched PubMed, Web of Science, Scopus, Cinahl and PsycINFO for ...Tieteelliset aikakauslehtiartikkelit
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Helppoa kuin mallinteko – lyhyt oppimäärä elinaikamallinnukseen ja ekstrapoloinnin aiheuttamaan epävarmuuteen taloudellisessa arvioinnissa
(Sosiaalilääketieteen yhdistys, 2023)Uusien lääkehoitojen kustannuksia ja terveyshyötyä tarkastellaan korvattavuus- tai käyttöönottopäätöstä tehtäessä terveystaloudellisen mallinnuksen avulla. Uusiin hoitoihin liittyvää tutkimusdataa on usein saatavilla ...
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Helteen vaikutukset ja varautuminen terveydenhuollossa
(Suomalainen lääkäriseura Duodecim, 2023)Kuuma sää ja helleaallot ovat merkittävä kansanterveydellinen riskitekijä erityisesti ikääntyneille ja pitkäaikaissairauksista kärsiville myös Suomessa. Ilmaston lämmetessä ja väestön ikääntyessä helteeseen liittyvät ...
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Hemoglobin level and lipoprotein particle size
(Springer Nature, 2018)Background Alterations in lipoprotein size are associated with increased cardiovascular disease risk. Higher hemoglobin levels may indicate a higher risk of atherosclerosis and was previously associated with obesity, ...Tieteelliset aikakauslehtiartikkelit
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The Hermeneutic Circle Helps to Accumulate Knowledge and Understanding: An Empirical Example of Public Health Nurses' Experiences of Supporting Multiple-birth Families
(David Publishing Company, 2017)In phenomenological research, the reduction is a complex reflective attentiveness required for phenomenological understanding. A literature review revealed that little research has been done on health care professionals ...info:eu-repo/semantics/article
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Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance
(Springer Nature, 2017)Finding new causes of monogenic diabetes helps understand glycaemic regulation in humans. To find novel genetic causes of maturity-onset diabetes of the young (MODY), we sequenced MODY cases with unknown aetiology and ...info:eu-repo/semantics/article
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Hexosome engineering for targeting of regional lymph nodes
(Elsevier BV, 2020)Hexosomes are nanoparticles enveloping inverted discontinuous hexagonal (HII) liquid crystalline phases that offer exceptional physicochemical characteristics for drug encapsulation and targeted drug delivery. However, the ...Tieteelliset aikakauslehtiartikkelit
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Hidden sources like saline flushes make a significant contribution to the fluid intake of very low birth weight infants during the first postnatal week
(Wiley, 2020)Aim We examined actual fluid intake, and routes of administration, in very low birthweight (VLBW) infants during the first week of life in a neonatal intensive care unit. Methods This retrospective cohort study comprised ...Tieteelliset aikakauslehtiartikkelit
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High fitness levels offset the increased risk of chronic obstructive pulmonary disease due to low socioeconomic status: A cohort study
(Elsevier BV, 2021)Objective Evidence suggests that higher cardiorespiratory fitness (CRF) levels can offset the increased risk of adverse outcomes due to other risk factors. The impact of high CRF levels on the increased risk of chronic ...Tieteelliset aikakauslehtiartikkelit
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High Leisure-Time Physical Activity Is Associated With Reduced Risk of Sudden Cardiac Death Among Men With Low Cardiorespiratory Fitness
(Elsevier BV, 2018)Background We studied the independent and joint associations of leisure-time physical activity (LTPA) and cardiorespiratory fitness (CRF) with the risk of sudden cardiac death (SCD) among middle-aged men. Methods The ...Tieteelliset aikakauslehtiartikkelit
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High levels of Butyrate and Propionate in early life are associated with protection against atopy
(Wiley, 2018)Background Dietary changes are suggested to play a role in the increasing prevalence of allergic diseases and asthma. Short‐chain fatty acids (SCFAs) are metabolites present in certain foods and are produced by microbes ...Tieteelliset aikakauslehtiartikkelit
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High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation
(Oxford University Press (OUP), 2015)Nucleoli are not only organelles that produce ribosomal subunits. They are also overarching sensors of different stress conditions and they control specific nucleolar stress pathways leading to stabilization of p53. During ...info:eu-repo/semantics/article
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High Mutation Burden of Circulating Cell-Free DNA in Early-Stage Breast Cancer Patients Is Associated With a Poor Relapse-Free Survival
(Wiley, 2020)Background High tumor mutation burden is shown to be associated with a poor clinical outcome. As the tumor‐derived fraction of circulating cell‐free DNA (cfDNA) is shown to reflect the genetic spectrum of the tumor, we ...Tieteelliset aikakauslehtiartikkelit
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High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy
(2017)Adenoviruses are very efficient vectors for delivering therapeutic genes in preclinical and clinical trials. However, randomized controlled human trials have often been lacking clear clinically relevant results. We ...info:eu-repo/semantics/article
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High-Fat Diet, Betaine, and Polydextrose Induce Changes in Adipose Tissue Inflammation and Metabolism in C57BL/6J Mice
(Wiley, 2018)Scope High‐fat diets are a likely cause of low‐grade inflammation and obesity‐related pathologies. This study measures the effects of a high‐fat diet, in combination with two dietary supplements—betaine and polydextrose—on ...Tieteelliset aikakauslehtiartikkelit
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High-level cytoplasmic claudin 3 expression is an independent predictor of poor survival in triple-negative breast cancer
(Springer Nature, 2018)Background The subtype of claudin-low breast cancer can be reliably determined only by gene-expression profiling. Attempts have been made to develop immunohistochemical surrogates, which nearly always focus on membranous ...Tieteelliset aikakauslehtiartikkelit
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High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium
(The Pathological Society of Great Britain and Ireland and John Wiley & Sons Ltd, 2016)Automated methods are needed to facilitate high-throughput and reproducible scoring of Ki67 and other markers in breast cancer tissue microarrays (TMAs) in large-scale studies. To address this need, we developed an automated ...info:eu-repo/semantics/article
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Higher Preimplantation Opioid Doses Associated With Long-Term Spinal Cord Stimulation Failure in 211 Patients With Failed Back Surgery Syndrome
(Wiley, 2020)Objective Spinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). We studied the effect of preimplantation opioid use on SCS outcome and the effect of SCS on opioid use during a ...Tieteelliset aikakauslehtiartikkelit
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Hippocampal Sclerosis and Epilepsy in Elderly Population
(OMICS Publishing Group, 2017)Objective: In temporal lobe epilepsy, hippocampal sclerosis (HS) and Alzheimer’s disease (AD) pathological alterations in the hippocampus are frequently observed. Methods: We assessed the clinicopathological characteristics ...info:eu-repo/semantics/article
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HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry
(Springer Science and Business Media LLC, 2021)The atypical antipsychotic clozapine is the only effective medication for treatment-resistant schizophrenia. However, it can also induce serious adverse drug reactions, including agranulocytosis and neutropenia. The mechanism ...Tieteelliset aikakauslehtiartikkelit