Now showing items 1-3 of 3

    • Autonomous control of cardiovascular reactivity in patients with episodic and chronic forms of migraine 

      Mamontov OV; Babayan L; Amelin AV; Giniatullin R; Kamshilin AA (SpringerOpen, 2016)
      Background The autonomous cardiovascular control can contribute to progression of migraine. However, current data on cardiovascular reactivity in migraine, especially severe forms, are essentially contradictory. The main ...

    • Chronic Pyruvate Supplementation Increases Exploratory Activity and Brain Energy Reserves in Young and Middle-Aged Mice 

      Koivisto, H; Leinonen, H; Puurula, M; Hafes, HS; Barrera, GA; Stridh, MH; Waagepetersen, HS; Tiainen, M; Soininen, P; Zilberter, Y; Tanila, H (Frontiers Research Foundation, 2016)
      Numerous studies have reported neuroprotective effects of pyruvate when given in systemic injections. Impaired glucose uptake and metabolism are found in Alzheimer’s disease (AD) and in AD mouse models. We tested whether ...

    • Common data elements and data management: Remedy to cure underpowered preclinical studies 

      Lapinlampi N; Melin E; Aronica E; Bankstahl JP; Becker A; Bernard C; Gorter JA; Gröhn O; Lipsanen A; Lukasiuk K; Löscher W; Paananen J; Ravizza T; Roncon P; Simonato M; Vezzani A; Kokaia M; Pitkänen A (Elsevier BV, 2016)
      Lack of translation of data obtained in preclinical trials to clinic has kindled researchers to develop new methodologies to increase the power and reproducibility of preclinical studies. One approach relates to harmonization ...