Browsing Terveystieteiden tiedekunta by Subject "3-phenylcoumarin"

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    • Structure-Activity Relationship Analysis of 3-Phenylcoumarin-Based Monoamine Oxidase B Inhibitors 

      Rauhamaki, Sanna; Postila, Pekka A; Niinivehmas, Sanna; Kortet, Sami; Schildt, Emmi; Pasanen, Mira; Manivannan, Elangovan; Ahinko, Mira; Koskimies, Pasi; Nyberg, Niina; Huuskonen, Pasi; Multamaki, Elina; Pasanen, Markku; Juvonen, Risto O; Raunio, Hannu; Huuskonen, Juhani; Pentikainen, Olli T (Frontiers Media SA, 2018)
      Monoamine oxidase B (MAO-B) catalyzes deamination of monoamines such as neurotransmitters dopamine and norepinephrine. Accordingly, small-molecule MAO-B inhibitors potentially alleviate the symptoms of dopamine-linked ...
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