Now showing items 1-1 of 1

    • In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs 

      Juvonen, Risto O; Heikkinen, Aki T; Kärkkäinen, Olli; Jehangir, Rabia; Huuskonen, Juhani; Troberg, Johanna; Raunio, Hannu; Pentikäinen, Olli T; Finel, Moshe (Elsevier BV, 2019)
      Beagle dog is a standard animal model for evaluating nonclinical pharmacokinetics of new drug candidates. Glucuronidation in intestine and liver is an important first-pass drug metabolic pathway, especially for phenolic ...
      Tieteelliset aikakauslehtiartikkelit