Now showing items 1-2 of 2

    • Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling 

      Walle P; Takkunen M; Männistö V; Vaittinen M; Käkelä P; Ågren J; Schwab U; Lindström J; Tuomilehto J; Uusitupa M; Pihlajamäki J. (Springer Nature, 2017)
      Background: The effects of obesity surgery on serum and adipose tissue fatty acid (FA) profile and FA metabolism may modify the risk of obesity-related diseases. Methods: We measured serum (n=122) and adipose tissue ...

    • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels 

      Kilpeläinen, TO; Carli, JF; Skowronski, AA; Sun, Q; Kriebel, J; Feitosa, MF; Hedman, ÅK; Drong, AW; Hayes, JE; Zhao, J; Pers, TH; Schick, U; Grarup, N; Kutalik, Z; Trompet, S; Mangino, M; Kristiansson, K; Beekman, M; Lyytikäinen, LP; Eriksson, J et al (Nature Publishing Group, 2016)
      Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency and severe ...