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    • Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease 

      Rinne JO; Wesnes K; Cummings JL; Hakulinen P; Hallikainen M; Hänninen J; Murphy M; Riordan H; Scheinin M; Soininen H; Rouru J (Elsevier BV, 2017)
      Introduction ORM-12741 is a novel selective antagonist of alpha-2C adrenoceptors. This trial evaluated the safety and efficacy of ORM-12741 in patients with Alzheimer's disease (AD). Methods A randomized, double-blind, ...