Browsing Terveystieteiden tiedekunta by Subject "thiol"

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    • Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis 

      Jobbagy, Soma; Vitturi, Dario A; Salvatore, Sonia R; Turell, Lucía; Pires, Maria F; Kansanen, Emilia; Batthyany, Carlos; Lancaster, Jack R Jr; Freeman, Bruce A; Schopfer, Francisco (Elsevier BV, 2019)
      Cells evolved robust homeostatic mechanisms to protect against oxidation or alkylation by electrophilic species. Glutathione (GSH) is the most abundant intracellular thiol, protects cellular components from oxidation and ...
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