Browsing Terveystieteiden tiedekunta by Subject "type 1 diabetes"
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Early childhood CMV infection may decelerate the progression to clinical type 1 diabetes
(Wiley, 2018)Aims/Hypothesis Evidence of the role of cytomegalovirus (CMV) infection in the pathogenesis of type 1 diabetes (T1D) has remained inconclusive. Our aim was to elucidate the possible role of CMV infection in the initiation ...Tieteelliset aikakauslehtiartikkelit
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FOXP3+ Regulatory T Cell Compartment Is Altered in Children With Newly Diagnosed Type 1 Diabetes but Not in Autoantibody-Positive at-Risk Children
(Frontiers Media SA, 2019)The dysfunction of FOXP3-positive regulatory T cells (Tregs) plays a key role in the pathogenesis of autoimmune diseases, including type 1 diabetes (T1D). However, previous studies analyzing the peripheral blood Treg ...Tieteelliset aikakauslehtiartikkelit
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No evidence of the role of early chemical exposure in the development of ß-cell autoimmunity
(Springer Nature America, Inc, 2018)Exposure to environmental chemicals can modulate the developing immune system, but its role in the pathogenesis of type 1 diabetes is largely unexplored. Our objective was to study the levels of circulating concentrations ...Tieteelliset aikakauslehtiartikkelit
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Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells
(Wiley, 2020)Dysfunction of FOXP3‐positive regulatory T cells (Tregs) likely plays a major role in the pathogenesis of multiple autoimmune diseases including type 1 diabetes (T1D). Whether genetic polymorphisms associated with the risk ...Tieteelliset aikakauslehtiartikkelit