Browsing Terveystieteiden tiedekunta by Title
Now showing items 1-20 of 179
-
25 years of advances in the definition, classification and treatment of status epilepticus
(Elsevier BV, 2016)Purpose Status epilepticus (SE) requires not only urgent symptomatic treatment with antiepileptic drugs but also rapid identification and treatment of its cause. This narrative review summarizes the most important advances ... -
A century of trends in adult human height
(eLife Sciences Organisation, Ltd., 2016)Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height ... -
A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs
(Springer Nature, 2016)Background Attention deficit hyperactivity disorder (ADHD) is a prevalent and multifactorial neuropsychiatric disorder in the human population worldwide. Complex etiology and clinical heterogeneity have challenged the ... -
Acute detachment of hexokinase II from mitochondria modestly increases oxygen consumption of the intact mouse heart
(Elsevier BV, 2017)Objective Cardiac hexokinase II (HKII) can translocate between cytosol and mitochondria and change its cellular expression with pathologies such as ischemia–reperfusion, diabetes and heart failure. The cardiac metabolic ... -
Adrenomedullin: a marker of impaired hemodynamics, organ dysfunction, and poor prognosis in cardiogenic shock
(Springer Nature, 2017)Background The clinical CardShock risk score, including baseline lactate levels, was recently shown to facilitate risk stratification in patients with cardiogenic shock (CS). As based on baseline parameters, however, it ... -
Angiogenic gene therapy in cardiovascular diseases: dream or vision?
(Oxford University Press (OUP), 2017)Chronic cardiovascular diseases are significant health problems. Although current treatment strategies have tremendously improved disease management, up to 30% of these patients cannot be successfully treated with current ... -
Are risk predicting models useful for estimating survival of patients with rheumatoid arthritis-associated interstitial lung disease?
(Springer NatureBritannia, 2017)Background Risk predicting models have been applied in idiopathic pulmonary fibrosis (IPF), but still not validated in patients with rheumatoid arthritis-associated interstitial lung disease (RA-ILD). The purpose of this ... -
Association of Forced Vital Capacity with the Developmental Gene NCOR2
(Public Library of Science, 2016)Background Forced Vital Capacity (FVC) is an important predictor of all-cause mortality in the absence of chronic respiratory conditions. Epidemiological evidence highlights the role of early life factors on adult FVC, ... -
Associations of Baltic Sea and Mediterranean dietary patterns with bone mineral density in elderly women
(Britannia, 2017)Dietary quality in relation to bone health has been analysed in relatively few studies. The current study aimed to assess the association of the Baltic Sea diet (BSD) and the Mediterranean diet (MD) with bone mineral density ... -
Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition
(Alankomaat, 2017)Background: CAIDE Dementia Risk Score is the first validated tool for estimating dementia risk based on a midlife risk profile. Objectives: This observational study investigated longitudinal associations of CAIDE Dementia ... -
Associations of estimated delta-5-desaturase and delta-6-desaturase activities with stroke risk factors and risk of stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study
(Cambridge University Press (CUP), 2017)Stroke is a leading cause of morbidity and mortality. The role of PUFA in reducing the risk of stroke is uncertain. The concentrations of PUFA in the human body are determined both by dietary intake and by activities of ... -
Associations of Objectively Measured Physical Activity and Sedentary Time With Arterial Stiffness in Pre-pubertal Children
(2017)Purpose: To investigate the relationships of objectively measured physical activity (PA) and sedentary time (ST) to arterial stiffness in pre-pubertal children. Method: Altogether 136 children (57 boys, 79 girls) aged ... -
Attention to nurses' rewarding - an interview study of registered nurses working in primary and private healthcare in Finland
(John Wiley & Sons Ltd, 2017)Aims and objectives To identify meaningful types of rewards and the consequences of rewards as expressed by Finnish registered nurses working in primary and private healthcare. Background Previous studies have found ... -
Atypical brain activation in children who stutter in a visual Go/Nogo task: An ERP study
(Elsevier BV, 2017)Objective The aim of the study was to investigate inhibitory control by evaluating possible differences in the strength and distribution of the brain activity in a visual Go/Nogo task in children who stutter (CWS) compared ... -
Autonomous control of cardiovascular reactivity in patients with episodic and chronic forms of migraine
(SpringerOpen, 2016)Background The autonomous cardiovascular control can contribute to progression of migraine. However, current data on cardiovascular reactivity in migraine, especially severe forms, are essentially contradictory. The main ... -
Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells
(MDPI AG, 2017)The impairment of autophagic and proteasomal cleansing together with changes in pigmentation has been documented in retinal pigment epithelial (RPE) cell degeneration. However, the function and co-operation of these ... -
Beneficial Effects of Regular Physical Exercises on Mental State in Visually Impaired and Deaf-blind Adults
(Horizon Research Publishing Corporation, 2016)The most common mental health problems in visually impaired and deaf-blind adults are depression, anxiety, tension, difficulties in falling asleep and disturbed sleep. The physical training program used in this study was ... -
Benefits of switching from latanoprost to preservative-free tafluprost eye drops: a meta-analysis of two Phase IIIb clinical trials
(Dove Medical Press Ltd., 2016)Introduction: Glaucoma patients frequently exhibit ocular surface side effects during treatment with prostaglandin eye drops. The present work investigated whether glaucoma patients suffering from signs and symptoms of ... -
Biological interpretation of genome-wide association studies using predicted gene functions
(Nature Publishing Group, 2015-01-19)The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions ... -
Cardiopulmonary Exercise Testing in Pediatrics
(American Thoracic Society, 2017)Aerobic fitness is an important determinant of overall health. Higher aerobic fitness has been associated with many health benefits. Because myocardial ischemia is rare in children, indications for exercise testing differ ...
