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dc.contributor.authorHarju, Maijakaisa
dc.contributor.authorKeski-Nisula, Leea
dc.contributor.authorGeorgiadis, Leena
dc.contributor.authorHeinonen, Seppo
dc.date.accessioned2016-10-12T12:05:49Z
dc.date.available2016-10-12T12:05:49Z
dc.date.issued2016
dc.identifier10.1186/s12889-016-3029-6fi_FI
dc.identifier.citationHarju, M., Keski-Nisula, L., Georgiadis, L., & Heinonen, S. (2016). Parental smoking and cessation during pregnancy and the risk of childhood asthma. BMC Public Health, 16, 428. http://doi.org/10.1186/s12889-016-3029-6fi_FI
dc.identifier.issn1471-2458
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/160
dc.descriptionArticle
dc.description.abstractBackground To evaluate the association between maternal and paternal smoking during pregnancy, and asthma among offspring. Methods We conducted a hospital-based birth retrospective observational birth cohort study in a University-based Obstetrics and Gynecology Department, Kuopio University Hospital, Finland. 39 306 women, delivering between 1989 and 2006, were linked to the national register for asthma reimbursement for their offspring (2641 asthmatics). Pregnancy factors were recorded during pregnancy. Results The risk of asthma was significantly elevated if both parents smoked (aOR 3.7; 95 % Cl 3.2-4.4) and it remained high in only paternal smoking families (aOR 2.9; 95 % Cl 2.5-3.3) as well as only maternal smoking families (aOR 1.7; 95 % Cl 1.2-2.2). Paternal cessation of smoking during pregnancy seemed to reduce the risk of asthma regardless of maternal smoking (aOR 0.3-0.4). Conclusions Parental smoking, and especially paternal smoking, was significantly associated with the risk of asthma in offspring and paternal cessation of smoking during pregnancy was associated with a decreased risk of childhood asthma regardless of maternal smoking. The results indicate that both parents should be encouraged to quit smoking during pregnancy, since it is a relatively easy and cheap way to reduce the risk of asthma in offspring.fi_FI
dc.language.isoENfi_FI
dc.publisherBioMed Central Ltd.fi_FI
dc.relation.ispartofseriesBMC PUBLIC HEALTH
dc.relation.urihttp://doi.org/10.1186/s12889-016-3029-6fi_FI
dc.rightsCC BY http://creativecommons.org/licenses/by/4.0/fi_FI
dc.subjectSmokingfi_FI
dc.subjectPregnancyfi_FI
dc.subjectChildhoodfi_FI
dc.subjectAsthmafi_FI
dc.subjectMaternalfi_FI
dc.subjectPaternalfi_FI
dc.subjectParentalfi_FI
dc.titleParental smoking and cessation during pregnancy and the risk of childhood asthmafi_FI
dc.typehttp://purl.org/eprint/type/JournalArticle
dc.rights.licenseDistributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)
dc.description.versionPublisher's pdffi_FI
dc.contributor.departmentFaculty of Health Sciences
dc.contributor.departmentSchool of Medicine / Clinical Medicine
uef.solecris.id41460289
eprint.statushttp://purl.org/eprint/status/PeerReviewedfi_FI
dc.type.publicationinfo:eu-repo/semantics/article
dc.rights.accessrights© Authors
dc.relation.doi10.1186/s12889-016-3029-6
dc.description.reviewstatushttp://purl.org/eprint/status/PeerReviewed
dc.relation.articlenumber428
dc.relation.issn1471-2458
dc.relation.volume16


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