Photoacoustic tomography setup using LED illumination

Abstract

Photoacoustic tomography (PAT) is a hybrid imaging modality that combines optical contrast with ultrasound resolution. Most of the PAT configurations are based on high-energy solid-state lasers such as Nd:YAG laser. In this work, a PAT system that uses light-emitting diode (LED) as a light source is introduced. The system is designed so that the imaged target can be stationary. The target is illuminated by a LED light source from one side and the pressure wave is measured using an acoustic transducer that is rotated around the target. Image reconstruction is based on Bayesian approach to ill-posed inverse problems. The system was tested with light absorbing targets also in limited-view and sparse angle measurement situations. The results show that LED-based instrumentation and advanced reconstruction methods can form a potential PAT system that can also be applied in limited-view and sparse angle photoacoustic tomography.