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dc.contributor.authorPiispala J
dc.contributor.authorMäättä S
dc.contributor.authorPääkkönen A
dc.contributor.authorBloigu R
dc.contributor.authorKallio M
dc.contributor.authorJansson-Verkasalo E
dc.date.accessioned2017-07-21T09:56:20Z
dc.date.available2017-07-21T09:56:20Z
dc.date.issued2017
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/3696
dc.description.abstractObjective The aim of the study was to investigate inhibitory control by evaluating possible differences in the strength and distribution of the brain activity in a visual Go/Nogo task in children who stutter (CWS) compared to typically developing children (TDC). Methods Eleven CWS and 19 TDC participated. Event related potentials (ERP) were recorded using a 64-channel EEG-cap during an equiprobable visual Go/Nogo task. The global field power (GFP) as well as the mean amplitudes in the P3 time frame were compared between groups. Additionally, the potential maps of the groups were investigated visually in the N2 and P3 time windows. Results The groups differed significantly in the right frontal area especially in the Nogo condition (p < 0.001) with CWS showing smaller (less positive) mean amplitudes, most likely due to a prolonged and asymmetrical N2 component. Also the fronto-central Nogo P3 component was rather indistinct in CWS, but easily recognizable in TDC in the potential maps. Conclusions The CWS show atypical brain activation compared to the TDC in a Go/Nogo task as indexed by the excessive N2-related activity in both conditions and reduced P3-related activity in Nogo condition. Significance These findings indicate atypical stimulus evaluation and response inhibition processes in CWS.en
dc.language.isoENen
dc.publisherElsevier BVen
dc.relation.ispartofseriesCLINICAL NEUROPHYSIOLOGYen
dc.relation.urihttp://dx.doi.org/10.1016/j.clinph.2016.11.006en
dc.rightsCC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectEvent related potentialen
dc.subjectGo/Nogoen
dc.subjectStimulus evaluationen
dc.subjectInhibitory controlen
dc.subjectChildrenen
dc.subjectStutteringen
dc.titleAtypical brain activation in children who stutter in a visual Go/Nogo task: An ERP studyen
dc.description.versionfinal draften
dc.contributor.departmentSchool of Medicine / Clinical Medicineen
uef.solecris.id47069372en
dc.type.publicationinfo:eu-repo/semantics/articleen
dc.rights.accessrights© International Federation of Clinical Neurophysiologyen
dc.relation.doi10.1016/j.clinph.2016.11.006en
dc.description.reviewstatuspeerRevieweden
dc.format.pagerange194-203en
dc.relation.issn1388-2457en
dc.relation.issue1en
dc.relation.volume128en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/acceptedVersionen


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