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dc.contributor.authorHoevenaar-Blom MP
dc.contributor.authorGuillemont J
dc.contributor.authorNgandu T
dc.contributor.authorBeishuizen CRL
dc.contributor.authorColey N
dc.contributor.authorMoll van Charante EP
dc.contributor.authorAndrieu S
dc.contributor.authorKivipelto M
dc.contributor.authorSoininen H
dc.contributor.authorBrayne C
dc.contributor.authorMeiller Y
dc.contributor.authorRichard E
dc.date.accessioned2017-09-15T10:35:26Z
dc.date.available2017-09-15T10:35:26Z
dc.date.issued2017
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/4284
dc.description.abstractLack of attention to missing data in research may result in biased results, loss of power and reduced generalizability. Registering reasons for missing values at the time of data collection, or—in the case of sharing existing data—before making data available to other teams, can save time and efforts, improve scientific value and help to prevent erroneous assumptions and biased results. To ensure that encoding of missing data is sufficient to understand the reason why data are missing, it should ideally be context-free. Therefore, 11 context-free codes of missing data were carefully designed based on three completed randomized controlled clinical trials and tested in a new randomized controlled clinical trial by an international team consisting of clinical researchers and epidemiologists with extended experience in designing and conducting trials and an Information System expert. These codes can be divided into missing due to participant and/or participation characteristics (n = 6), missing by design (n = 4), and due to a procedural error (n = 1). Broad implementation of context-free missing data encoding may enhance the possibilities of data sharing and pooling, thus allowing more powerful analyses using existing dataen
dc.language.isoENen
dc.relation.ispartofseriesPLOS ONEen
dc.relation.urihttp://dx.doi.org/10.1371/journal.pone.0182362en
dc.rightsCC BY http://creativecommons.org/licenses/by/4.0/en
dc.titleImproving data sharing in research with context-free encoded missing dataen
dc.description.versionpublished versionen
dc.contributor.departmentSchool of Medicine / Clinical Medicineen
uef.solecris.id49503133en
dc.type.publicationinfo:eu-repo/semantics/articleen
dc.rights.accessrights© Hoevenaar-Blom et al.en
dc.relation.doi10.1371/journal.pone.0182362en
dc.description.reviewstatuspeerRevieweden
dc.relation.articlenumbere0182362
dc.relation.issn1932-6203en
dc.relation.issue9en
dc.relation.volume12en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
uef.solecris.openaccessOpen access -julkaisukanavassa ilmestynyt julkaisu


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