Show simple item record

dc.contributor.authorTurhanen Petri
dc.date.accessioned2018-01-10T13:33:30Z
dc.date.available2018-01-10T13:33:30Z
dc.date.issued2017
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/5152
dc.description.abstractThe chemical synthesis of a adenosine triphosphate analogue, 1-adenosin-5′-yl 3-(3-methylbut-2-enyl) triphosphoric acid diester (ApppD), is described. ApppD is known to be an active metabolite of the mevalonate pathway in the human body like its structural isomer isopentenyl ester of ATP (ApppI). Very recently, ApppI has been found to possess novel function(s); now it will also be possible to examine the effects of ApppD more precisely because it can be synthesized in reasonable amounts. 1-Adenosin-5′-yl 3-(3-methylbut-2-enyl) diphosphoric acid diester (AppD; a adenosine diphosphate analogue) was also isolated from the synthesis mixture. Both ApppD and AppD were characterized by 1H, 13C, 31P NMR and mass spectrometry methods.en
dc.language.isoENen
dc.publisherAmerican Chemical Society (ACS)en
dc.relation.ispartofseriesACS Omegaen
dc.relation.urihttp://dx.doi.org/10.1021/acsomega.7b00531en
dc.rightsACS AuthorChoice Licenseen
dc.titleSynthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppDen
dc.description.versionpublished versionen
dc.contributor.departmentSchool of Pharmacy, Activitiesen
uef.solecris.id49391240en
dc.type.publicationinfo:eu-repo/semantics/articleen
dc.rights.accessrights© American Chemical Societyen
dc.relation.doi10.1021/acsomega.7b00531en
dc.description.reviewstatuspeerRevieweden
dc.format.pagerange2835-2838en
dc.relation.issn2470-1343en
dc.relation.issue6en
dc.relation.volume2en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
uef.solecris.openaccessOpen access -julkaisukanavassa ilmestynyt julkaisu


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record