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dc.contributor.authorLehto Lauri J
dc.contributor.authorIdiyatullin Djaudat
dc.contributor.authorZhang Jinjin
dc.contributor.authorUtecht Lynn
dc.contributor.authorAdriany Gregor
dc.contributor.authorGarwood Michael
dc.contributor.authorGröhn Olli
dc.contributor.authorMichaeli Shalom
dc.contributor.authorMangia Silvia
dc.date.accessioned2018-01-12T09:03:55Z
dc.date.available2018-01-12T09:03:55Z
dc.date.issued2017
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/5164
dc.description.abstractRecently introduced 3D radial MRI pulse sequence entitled Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) having virtually zero acquisition delay was used to obtain functional MRI (fMRI) contrast in rat's brain at 9.4 T during deep brain stimulation (DBS). The results demonstrate that MB-SWIFT allows functional images free of susceptibility artifacts, and provides an excellent fMRI activation contrast in the brain. Flip angle dependence of the MB-SWIFT fMRI signal and elimination of the fMRI contrast while using saturation bands, indicate a blood flow origin of the observed fMRI contrast. MB-SWIFT fMRI modality permits activation studies in the close proximity to an implanted lead, which is not possible to achieve with conventionally used gradient echo and spin echo - echo planar imaging fMRI techniques. We conclude that MB-SWIFT fMRI is a powerful imaging modality for investigations of functional responses during DBS.en
dc.language.isoENen
dc.publisherElsevier BVen
dc.relation.ispartofseriesNEUROIMAGEen
dc.relation.urihttp://dx.doi.org/10.1016/j.neuroimage.2017.08.012en
dc.rightsCC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectMulti-band SWIFTen
dc.subjectfMRIen
dc.subjectZero-TE fMRIen
dc.subjectBlood flowen
dc.subjectDeep brain stimulationen
dc.titleMB-SWIFT functional MRI during deep brain stimulation in ratsen
dc.description.versionpublished versionen
dc.contributor.departmentA.I. Virtanen -instituuttien
uef.solecris.id49391550en
dc.type.publicationinfo:eu-repo/semantics/articleen
dc.rights.accessrights© Authorsen
dc.relation.projectidinfo:eu-repo/grantAgreement/EC/H2020-EU.1.3.3./691110/EU/Advanced MR methods for characterization of microstructural brain damage/MICROBRADAMen
dc.relation.doi10.1016/j.neuroimage.2017.08.012en
dc.description.reviewstatuspeerRevieweden
dc.format.pagerange443-448en
dc.relation.issn1053-8119en
dc.relation.volume159en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
uef.solecris.openaccessOpen access -julkaisukanavassa ilmestynyt julkaisu


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