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dc.contributor.authorSchwab, Ursula Sonja
dc.contributor.authorErkkilä, Arja
dc.contributor.authorKurl, Sudhir
dc.contributor.authorLankinen, Maria
dc.contributor.authorde Mello Laaksonen, Vanessa
dc.date.accessioned2018-02-21T09:37:34Z
dc.date.available2018-02-21T09:37:34Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6124
dc.description.abstractScope The aim of the study is to examine whether lean fish (LF), fatty fish (FF), and camelina sativa oil (CSO), a plant-based source of alpha-linolenic acid (ALA), differ in their metabolic effects in subjects with impaired glucose metabolism. Methods and results Altogether 79 volunteers with impaired fasting glucose, BMI 25–36 kg m–2, age 43–72 years, participated in a 12-week randomized controlled trial with four parallel groups, that is, the FF (four fish meals/week), LF (four fish meals/week), CSO (10 g d–1 ALA), and control (limited intakes of fish and sources of ALA) groups. The proportions of eicosapentaenoic acid and DHA increase in plasma lipids in the FF group, and the proportion of ALA increase in the CSO group (p < 0.0001 for all). In the CSO group, total and LDL-cholesterol (C) concentrations decrease compared with the FF and LF groups; LDL-C/HDL-C and ApoB/ApoA-I ratios decrease compared with the LF group. There are no significant changes in glucose metabolism or markers of low-grade inflammation. Conclusions A diet enriched in CSO improves serum lipid profile as compared with a diet enriched in FF or LF in subjects with impaired fasting glucose, with no differences in glucose metabolism or concentrations of inflammatory markers.en
dc.language.isoENen
dc.publisherWiley-Blackwellen
dc.relation.ispartofseriesMolecular Nutrition & Food Researchen
dc.relation.urihttp://dx.doi.org/10.1002/mnfr.201700503en
dc.rightsAll rights reserveden
dc.titleCamelina Sativa Oil, but not Fatty Fish or Lean Fish, Improves Serum Lipid Profile in Subjects with Impaired Glucose Metabolism - A Randomized Controlled Trialen
dc.description.versionfinal draften
dc.contributor.departmentFaculty of Health Sciences, shared activities,School of Medicine / Clinical Medicineen
uef.solecris.id51565723en
dc.type.publicationarticleen
dc.rights.accessrights© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheimen
dc.relation.doi10.1002/mnfr.201700503en
dc.description.reviewstatuspeerRevieweden
dc.publisher.countryENen
dc.relation.articlenumber1700503en
dc.relation.issn1613-4125en
dc.relation.issue4en
dc.relation.volume62en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/acceptedVersionen


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