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dc.contributor.authorLiimatta, J
dc.contributor.authorSintonen, H
dc.contributor.authorUtriainen, P
dc.contributor.authorVoutilainen, R
dc.contributor.authorJääskeläinen, J
dc.date.accessioned2018-04-23T06:57:17Z
dc.date.available2018-04-23T06:57:17Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6528
dc.description.abstractBackground/Aim: Children with premature adrenarche (PA) are taller and more overweight than their healthy peers, and PA girls have a slightly accelerated pubertal development. There is some evidence that early exposure to androgens may have an influence on psychosocial development. The aim of this cross-sectional case-control study was to evaluate health-related quality of life (HRQoL) in PA children at the age of 12 years. Methods: The HRQoL was assessed for 43 PA (36 girls) and 63 control children (52 girls) at the median age of 12.0 years using the standardized 16D instrument, and the scores of the PA children were compared to those of the control children and reference population. Results: The mean overall HRQoL scores did not differ between PA and control girls, PA and control boys, or all PA and control children or the reference population. Independently of PA, overweight girls had a lower mean overall HRQoL score than lean girls, and both overweight girls and boys were on average worse off on the dimension of appearance than their lean peers. Conclusions: PA children have as good self-rated HRQoL as their peers at the age of 12 years. Overweight is associated with a worse HRQoL profile independently of PA.
dc.language.isoEN
dc.publisherS. Karger AG
dc.relation.ispartofseriesHORMONE RESEARCH IN PAEDIATRICS
dc.relation.urihttp://dx.doi.org/10.1159/000487134
dc.rightsAll rights reserved
dc.titleChildren with a History of Premature Adrenarche Have Good Health-Related Quality of Life at the Age of 12 Years
dc.description.versionfinal draft
dc.contributor.departmentSchool of Medicine / Clinical Medicine
uef.solecris.id53585438en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© S. Karger AG
dc.relation.doi10.1159/000487134
dc.description.reviewstatuspeerReviewed
dc.format.pagerange184-188
dc.publisher.countrySveitsi
dc.relation.issn1663-2818
dc.relation.issue3
dc.relation.volume89
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessEi


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