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Consensus guidelines for the use and interpretation of angiogenesis assays

dc.contributor.authorNowak-Sliwinska, P
dc.contributor.authorAlitalo, K
dc.contributor.authorAllen, E
dc.contributor.authorAnisimov, A
dc.contributor.authorAplin, AC
dc.contributor.authorAuerbach, R
dc.contributor.authorAugustin, HG
dc.contributor.authorBates, DO
dc.contributor.authorvan Beijnum, JR
dc.contributor.authorBender, RHF
dc.contributor.authorBergers, G
dc.contributor.authorBikfalvi, A
dc.contributor.authorBischoff, J
dc.contributor.authorBöck, BC
dc.contributor.authorBrooks, PC
dc.contributor.authorBussolino, F
dc.contributor.authorCakir, B
dc.contributor.authorCarmeliet, P
dc.contributor.authorCastranova, D
dc.contributor.authorCimpean, AM
dc.contributor.authoret al [Incl Yläherttuala, Seppo; Nurro, Jussi]
dc.date.accessioned2018-05-23T05:54:11Z
dc.date.available2018-05-23T05:54:11Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6640
dc.description.abstractThe formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.
dc.language.isoenglanti
dc.publisherSpringer Nature
dc.relation.ispartofseriesAngiogenesis
dc.relation.urihttp://dx.doi.org/10.1007/s10456-018-9613-x
dc.rightsCC BY 4.0
dc.subjectangiogenesis
dc.subjectaortic ring
dc.subjectendothelial cell migration
dc.subjectproliferation
dc.subjectmicrofluidic
dc.subjectzebrafish
dc.subjectchorioallantoic membrane (CAM)
dc.subjectvascular network
dc.subjectintussusceptive angiogenesis
dc.subjectretinal vasculature
dc.subjectcorneal angiogenesis
dc.subjecthindlimb ischemia
dc.subjectmyocardial angiogenesis
dc.subjectrecombinant proteins
dc.subjecttip cells
dc.subjectplug assay
dc.subjectmyocardial angiogenesis
dc.subjectvessel co-option
dc.titleConsensus guidelines for the use and interpretation of angiogenesis assays
dc.description.versionpublished version
dc.contributor.departmentA.I. Virtanen -instituutti
uef.solecris.id54570660en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.relation.projectidinfo:eu-repo/grantAgreement/EC/H2020-EU.1.1./680209/EU/Optimized drug combinations for effective cancer treatment: a personalised approach/OPTIM
dc.relation.projectidinfo:eu-repo/grantAgreement/EC/FP7-IDEAS-ERC/269073/EU/Targeting endothelial metabolism: a novel anti-angioge
dc.relation.doi10.1007/s10456-018-9613-x
dc.description.reviewstatuspeerReviewed
dc.publisher.countryAlankomaat
dc.relation.issn0969-6970
dc.relation.volumeFirst Online: 15 May 2018
dc.rights.accesslevelopenAccess
dc.type.okmA2
uef.solecris.openaccessHybridijulkaisukanavassa ilmestynyt avoin julkaisu
dc.rights.copyright© Authors
dc.type.displayTypearticleen
dc.type.displayTypeartikkelifi
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/


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