Show simple item record

dc.contributor.authorHytönen, Jarkko P
dc.contributor.authorTaavitsainen, Jouni
dc.contributor.authorTarvainen, Santeri
dc.contributor.authorYlä-Herttuala, Seppo
dc.date.accessioned2018-08-14T10:55:09Z
dc.date.available2018-08-14T10:55:09Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6784
dc.description.abstractAngioplasty and stenting are standard treatment options for both stabile occlusive coronary artery disease and acute myocardial infarctions. Over the last years, several biodegradable stent systems have entered pre-clinical and clinical evaluation and into clinical practice. A strong supporting scaffold is necessary after angioplasty to prevent elastic recoil of the vessel but in the long term a permanent metallic stent will only impair normal physiology of the artery wall. Thus, the main advantage of a resorbable system is the potential for better vessel recovery and function in the long term. The new stent systems differ from traditional stents in size and biological responses and questions have risen regarding their mechanical strength and increased risk of stent thrombosis. Here, we present current treatment options with biodegradable scaffolds, discuss further key areas for improvements and review novel technological advances in the context of all up-to-date clinical trial information. New material choices are also covered as well as special considerations for pre-clinical testing.
dc.language.isoenglanti
dc.publisherOxford University Press (OUP)
dc.relation.ispartofseriesCARDIOVASCULAR RESEARCH
dc.relation.urihttp://dx.doi.org/10.1093/cvr/cvy097
dc.rightsAll rights reserved
dc.subjectbiodegradable stents
dc.subjectbioresorbable materials
dc.subjectcoronary stenting
dc.titleBiodegradable coronary scaffolds - their future and clinical and technological challenges
dc.description.versionfinal draft
dc.contributor.departmentA.I. Virtanen -instituutti
uef.solecris.id54221439en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Authors
dc.relation.doi10.1093/cvr/cvy097
dc.description.reviewstatuspeerReviewed
dc.format.pagerange1063-1072
dc.relation.issn0008-6363
dc.relation.issue8
dc.relation.volume114
dc.rights.accesslevelopenAccess
dc.type.okmA2
uef.solecris.openaccessEi


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record