Behavioral outcome measures to improve experimental stroke research
Tiedosto(t)
Rinnakkaistallenteen versio
final draftPäivämäärä
2018Tekijä(t)
Yksilöllinen tunniste
10.1016/j.bbr.2017.07.039Metadata
Näytä kaikki kuvailutiedotLisätietoa
Rinnakkaistallenne
Viittaus
Balkaya, Mustafa G. Trueman, Rebecca C. Boltze, Johannes. Corbett, Dale. Jolkkonen, Jukka. (2018). Behavioral outcome measures to improve experimental stroke research. BEHAVIOURAL BRAIN RESEARCH, 352, 161-171. 10.1016/j.bbr.2017.07.039.Oikeudet
Tiivistelmä
Functional recovery after an experimental stroke can be assessed by multiple behavioral tests, however, there is no consensus about which test to use in long-term stroke recovery studies or whether the tests are affected by stroke surgery, post-operative care or behavioral compensation due to repeated testing. This review describes the tests most commonly used to assess motor and sensorimotor function, cognition and mood in stroke animals. Although it is difficult to predict the direction of future research, it may be possible to prevent false-positive results by selecting an appropriate task or a battery of tasks. It is also expected that the upcoming stroke recovery recommendations and the improved dialogue between academy, industry and healthcare professionals will further promote translational success.
Avainsanat
Linkki alkuperäiseen julkaisuun
http://dx.doi.org/10.1016/j.bbr.2017.07.039Julkaisija
Elsevier BVKokoelmat
- Terveystieteiden tiedekunta [1735]