Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials

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Date
2018
Author(s)
Scala, Giovanni
Marwah, Veer
Kinaret, Pia
Sund, Jukka
Fortino, Vittorio
Greco, Dario
Unique identifier
10.1016/j.dib.2018.05.107
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Scala, Giovanni. Marwah, Veer. Kinaret, Pia. Sund, Jukka. Fortino, Vittorio. Greco, Dario. (2018). Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials.  Data in Brief, 19, 1046-1057. 10.1016/j.dib.2018.05.107.
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Abstract

We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h.

In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure.

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https://erepo.uef.fi/handle/123456789/6832
Link to the original item
http://dx.doi.org/10.1016/j.dib.2018.05.107
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Elsevier BV
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