Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
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CitationScala, Giovanni. Marwah, Veer. Kinaret, Pia. Sund, Jukka. Fortino, Vittorio. Greco, Dario. (2018). Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials. Data in Brief, 19, 1046-1057. 10.1016/j.dib.2018.05.107.
We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h.
In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure.
Link to the original itemhttp://dx.doi.org/10.1016/j.dib.2018.05.107
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