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dc.contributor.authorKunutsor, Setor K
dc.contributor.authorLaukkanen, Tanjaniina
dc.contributor.authorLaukkanen, Jari A
dc.date.accessioned2018-09-03T10:21:36Z
dc.date.available2018-09-03T10:21:36Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6896
dc.description.abstractPurpose: We sought to determine cross-sectional and longitudinal associations of frequency of sauna bathing with high sensitivity C-reactive protein (hsCRP), fibrinogen, leucocyte count and gamma-glutamyltransferase (GGT). Design: Baseline sauna bathing habits were assessed in 2269 men aged 42–61 years. Concentrations of hsCRP, fibrinogen, leucocyte count, and GGT were determined at baseline and 11 years later. The associations of sauna bathing frequency with baseline and 11-year hsCRP, fibrinogen, leucocyte count, and GGT levels were examined using robust multivariate regression analyses. Results: In baseline analysis, 4–7 sauna sessions/week (compared with 1 sauna session/week) was associated with −0.84 mg/l (95% CI, −1.55, −0.14; p = .019) lower hsCRP; −0.07 g/l (95% CI, −0.15, 0.02; p = .112) lower fibrinogen; and −0.28 × 109/l (95% CI, −0.51, −0.06; p = .015) lower leucocyte count, after multivariable adjustment. In longitudinal analysis, the corresponding estimates were −1.66 mg/l (95% CI, −3.13, −0.19; p = .027); −0.16 g/l (95% CI, −0.31, −0.02; p = .031); and −0.49 × 109/l (95% CI, −0.85, −0.14; p = .007) respectively. Sauna bathing frequency was not associated with GGT at baseline and 11 years. Conclusion: Observational evidence supports the hypothesis that reduction in inflammation may be one of the pathways linking frequent sauna bathing with decreased risk of acute and chronic disease conditions.
dc.language.isoenglanti
dc.publisherInforma UK Limited
dc.relation.ispartofseriesAnnals of Medicine
dc.relation.urihttp://dx.doi.org/10.1080/07853890.2018.1489143
dc.rightsAll rights reserved
dc.subjectsauna bathing
dc.subjectinflammation
dc.subjectoxidative stress
dc.subjectcohort study
dc.titleLongitudinal associations of sauna bathing with inflammation and oxidative stress: The KIHD prospective cohort study
dc.description.versionfinal draft
dc.contributor.departmentSchool of Medicine / Public Health
uef.solecris.id55096031en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Informa UK Limited, trading as Taylor & Francis Group
dc.relation.doi10.1080/07853890.2018.1489143
dc.description.reviewstatuspeerReviewed
dc.format.pagerange437-442
dc.publisher.countryBritannia
dc.relation.issn0785-3890
dc.relation.issue5
dc.relation.volume50
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessEi


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