Peak oxygen uptake, ventilatory threshold, and arterial stiffness in adolescents
Self archived versionfinal draft
MetadataShow full item record
CitationHaapala, EA. Laukkanen, JA. Takken, T. Kujala, UM. Finni, T. (2018). Peak oxygen uptake, ventilatory threshold, and arterial stiffness in adolescents. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, First Online: 11 August 2018, 10.1007/s00421-018-3963-3.
To investigate the associations of peak oxygen uptake (V˙O2peak) and V˙O2 at ventilatory threshold (V˙O2at VT) with arterial stiffness in adolescents.
The participants were 55 adolescents (36 girls, 19 boys) aged 16–19 years. Aortic pulse wave velocity (PWVao) and augmentation index (AIx%) were measured by non-invasive oscillometric device from right brachial artery level. V˙O2peakwas directly measured during a maximal ramp test on a cycle ergometer. V˙O2 at VT was determined using the equivalents for ventilation (V˙E/V˙CO2 and V˙E/V˙O2). V˙O2peak and V˙O2 at VT were normalised for body mass (BM) and lean mass (LM). Data were analysed using linear regression analyses and analysis of covariance adjusted for age and sex.
V˙O2peak normalised for BM (β = − 0.445, 95% CI − 0.783 to − 0.107) and V˙O2peak normalised for LM (β = − 0.386, 95% CI − 0.667 to − 0.106) were inversely associated with PWVao. A higher V˙O2 at VT normalised for BM (β = − 0.366, 95% CI − 0.646 to − 0.087) and LM (β = − 0.321, 95% CI − 0.578 to − 0.064) was associated with lower PWVao. Adolescents in the lowest third of V˙O2peak by LM (6.6 vs. 6.1 m/s, Cohen’s d = 0.33) and V˙O2 at VT by LM (6.6 vs. 6.0 m/s, Cohen’s d = 0.33) had a higher PWVao than those in the highest third of V˙O2peak or V˙O2 at VT by LM.
Higher V˙O2peak and V˙O2 at VT by BM and LM were related to lower arterial stiffness in adolescents. Normalising V˙O2peak and V˙O2 at VT for LM would provide the most appropriate measure of cardiorespiratory fitness in relation to arterial stiffness.
Subjectscardiorespiratory fitness physical fitness vascular stiffness arteriosclerosis adolescent
Link to the original itemhttp://dx.doi.org/10.1007/s00421-018-3963-3
PublisherSpringer Nature America, Inc
- Terveystieteiden tiedekunta