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dc.contributor.authorKoistinen, VM
dc.contributor.authorda Silva, AB
dc.contributor.authorAbrankó, L
dc.contributor.authorLow, D
dc.contributor.authorVillalba, RG
dc.contributor.authorBarberán, FT
dc.contributor.authorLandberg, R
dc.contributor.authorSavolainen, O
dc.contributor.authorAlvarez-Acero, I
dc.contributor.authorde Pascual-Teresa, S
dc.contributor.authorVan Poucke, C
dc.contributor.authorAlmeida, C
dc.contributor.authorPetrásková, L
dc.contributor.authorValentová, K
dc.contributor.authorDurand, S
dc.contributor.authorWiczkowski, W
dc.contributor.authorSzawara-Nowak, D
dc.contributor.authorGonzález-Domínguez, R
dc.contributor.authorLlorach, R
dc.contributor.authorAndrés-Lacueva, C
dc.contributor.authorAura, AM
dc.contributor.authorSeppänen-Laakso, T
dc.contributor.authorHanhineva, K
dc.contributor.authorManach, C
dc.contributor.authorBronze M
dc.date.accessioned2018-09-25T11:34:03Z
dc.date.available2018-09-25T11:34:03Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6976
dc.description.abstractBioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota and endogenous metabolism, represent thousands of chemical structures of potential interest for human nutrition and health. State-of-the-art analytical methodologies, including untargeted metabolomics based on high-resolution mass spectrometry, are required for the profiling of these compounds in complex matrices, including plant food materials and biofluids. The aim of this project was to compare the analytical coverage of untargeted metabolomics methods independently developed and employed in various European platforms. In total, 56 chemical standards representing the most common classes of bioactive compounds spread over a wide chemical space were selected and analyzed by the participating platforms (n = 13) using their preferred untargeted method. The results were used to define analytical criteria for a successful analysis of plant food bioactives. Furthermore, they will serve as a basis for an optimized consensus method.
dc.language.isoenglanti
dc.publisherMDPI AG
dc.relation.ispartofseriesMetabolites
dc.relation.urihttp://dx.doi.org/10.3390/metabo8030046
dc.rightsCC BY http://creativecommons.org/licenses/by/4.0/
dc.subjectphytochemicals
dc.subjectmass spectrometry
dc.subjectmethod development
dc.titleInterlaboratory Coverage Test on Plant Food Bioactive Compounds and their Metabolites by Mass Spectrometry-Based Untargeted Metabolomics
dc.description.versionpublished version
dc.contributor.departmentSchool of Medicine / Clinical Nutrition
uef.solecris.id56925802en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Authors
dc.relation.doi10.3390/metabo8030046
dc.description.reviewstatuspeerReviewed
dc.publisher.countrySveitsi
dc.relation.articlenumber46
dc.relation.issue3
dc.relation.volume8
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessOpen access -julkaisukanavassa ilmestynyt julkaisu


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