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dc.contributor.authorHamada, Nobuyki
dc.contributor.authorSalomaa, Sisko
dc.contributor.authorDörr, Wolfgang
dc.date.accessioned2018-11-26T10:15:34Z
dc.date.available2018-11-26T10:15:34Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/7175
dc.description.abstractPurpose: From radiation protection viewpoints, there have been continued discussions on potential individual differences in ionizing radiation responses. In October 2017, the International Commission on Radiological Protection (ICRP) and the European Radiological Protection Research Week (ERPW) held a joint meeting, of which key focus areas included individual responses. In March 2018, the European programs MELODI and CONCERT held a joint meeting on individual responses. This paper provides some highlights from these two meetings, and also briefly discusses pertinent issues on the tolerance dose concept used in radiation therapy vs the threshold dose concept used in radiation protection, a need of a longer follow up after exposure to lower doses and potential variations of individual responses depending on the levels of severity and onset time for tissue reactions, and radiomics. Conclusions: There remains a long way ahead before a somewhat more individualized approach will be implemented in the radiation protection system, but discussions towards individualized strategies may be useful, such as for protection of medical patients, emergency workers, and astronauts, among which medicine will lead the way. Strategies to incorporate the individualized approach need to be considered, along with further developments of scientific knowledge and ethical foundations.
dc.language.isoenglanti
dc.publisherInforma UK Limited
dc.relation.ispartofseriesINTERNATIONAL JOURNAL OF RADIATION BIOLOGY
dc.relation.urihttp://dx.doi.org/10.1080/09553002.2018.1513178
dc.rightsAll rights reserved
dc.subjectindividual response to ionizing radiation
dc.subjectcancer
dc.subjecttissue reactions
dc.subjectradiation protection
dc.subjectradiotherapy
dc.titleToward tailoring radiation protection strategies at an individual level
dc.description.versionfinal draft
dc.contributor.departmentYmpäristö- ja biotieteiden laitos / Toiminta
uef.solecris.id57580781en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Taylor & Francis Group, LLC
dc.relation.doi10.1080/09553002.2018.1513178
dc.description.reviewstatuspeerReviewed
dc.relation.issn0955-3002
dc.relation.volume[Published online: 27 Sep 2018]
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessEi


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