Show simple item record

dc.contributor.authorTajik, Behnam
dc.contributor.authorKurl, Sudhir
dc.contributor.authorTuomainen, Tomi-Pekka
dc.contributor.authorVirtanen, Jyrki K
dc.date.accessioned2019-02-19T12:13:32Z
dc.date.available2019-02-19T12:13:32Z
dc.date.issued2016
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/7460
dc.description.abstractLong-chain n-3 PUFA from fish and exercise capacity are associated with CVD risk. Fish, especially large and old predatory fish, may contain Hg, which may attenuate the inverse association of long-chain n-3 PUFA with CVD. However, the associations of long-chain n-3 PUFA or Hg exposure with exercise capacity are not well known. We aimed to evaluate the associations of serum long-chain n-3 PUFA EPA, docosapentaenoic acid (DPA) and DHA and hair Hg with exercise cardiac power (ECP, a ratio of VO2max:maximal systolic blood pressure (SBP) during an exercise test), a measure for exercise capacity. For this, data from the population-based Kuopio Ischaemic Heart Disease Risk Factor Study were analysed cross-sectionally in order to determine the associations between serum long-chain n-3 PUFA, hair Hg and ECP in 1672 men without CVD, aged 42–60 years. After multivariate adjustments, serum total long-chain n-3 PUFA concentration was associated with higher ECP and VO2max (P trend across quartiles=0·04 and P trend=0·02, respectively), but not with maximal SBP (P trend=0·69). Associations were generally similar when EPA, DPA and DHA were evaluated individually. Hair Hg was not associated with ECP, VO2max or maximal SBP. However, the associations of total long-chain n-3 PUFA (P interaction=0·03) and EPA (P interaction=0·02) with higher VO2max were stronger among men with lower hair Hg. Higher serum long-chain n-3 PUFA concentration, mainly a marker for fish consumption in this study population, was associated with higher ECP and VO2max in middle-aged men from eastern Finland.en
dc.language.isoenglantien
dc.publisherCambridge University Pressen
dc.relation.ispartofseriesBritish journal of nutritionen
dc.relation.urihttp://doi.org/10.1017/S0007114516002142en
dc.rightsAll rights reserveden
dc.subjectfatty acidsen
dc.subjectexercise capacityen
dc.subjectcohort studiesen
dc.subjectcross-sectional studyen
dc.titleThe association of serum long-chain n-3 PUFA and hair mercury with exercise cardiac power in menen
dc.description.versionpublished versionen
dc.contributor.departmentLääketieteen laitos / Kansanterveystiedeen
uef.solecris.id42211846en
dc.type.publicationarticleen
dc.rights.accessrights© Authorsen
dc.relation.doi10.1017/S0007114516002142en
dc.description.reviewstatuspeerRevieweden
dc.format.pagerange487-495en
dc.relation.issn0007-1145en
dc.relation.issue3en
dc.relation.volume116en
dc.rights.accesslevelopenAccessen
dc.type.okmA1en
dc.type.versioninfo:eu-repo/semantics/publishedVersionen


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record