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dc.contributor.authorAl-Ani, Anas Aaqel Salim Salim
dc.contributor.authorMutluay, Murat
dc.contributor.authorTjaderhane, Leo
dc.contributor.authorTezvergil-Mutluay, Arzu
dc.date.accessioned2019-04-10T05:32:12Z
dc.date.available2019-04-10T05:32:12Z
dc.date.issued2019
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/7528
dc.description.abstractThe purpose of this in vitro study was to evaluate and compare the effect of dimethyl sulfoxide (DMSO) or ethanol on the permeability, stiffness and collagen dissociation of demineralized dentin. Dentin cubes (2 × 2 × 2 mm) were demineralized in EDTA and incubated in DMSO or ethanol (0.01, 0.1, 1, 5, 10, 20, 50 and 100%) (n= 10/group) for 30 s, followed by 100% HEMA incubation. Extracted HEMA was quantified. For elastic modulus (E), demineralized dentin beams (6 × 2 × 1 mm) were incubated in DMSO or ethanol (1, 10, 20, 50 and 100%) for 10, 30 or 60 min at 3-point bending. Additional demineralized dentin discs (1 mm) were incubated in DMSO (1, 10, 50 and 100%) for 10, 30 and 60 min and the optical clearing effect was observed. The data were analyzed using ANOVA and Tukey's test (α=0.05) using SigmaPlot (Systat Software Inc., San Jose, CA). Compared to controls, HEMA uptake was significantly higher with all DMSO concentrations, and with 0.1% or higher ethanol concentrations (p<0.05). HEMA uptake in DMSO-incubated specimens (0.01, 5 and 10%) was significantly higher than with the ethanol incubation. Significant increase in elastic moduli was observed with 50–100% DMSO- and only with 100% ethanol after 10 min incubation. The optical clearing effect of 50–100% DMSO-incubated dentin disks was observed starting from 10 min. The pretreatment of dentin surfaces with low concentrations of DMSO resulted in significant improvement of the penetration of monomers to demineralized dentin matrices. Increase in penetration of monomers combined with a reversible stiffening of dentin collagenous matrix may explain the previously shown increase in durability of wet- or dry-bonded adhesive interfaces with DMSO treatment.
dc.language.isoenglanti
dc.publisherElsevier BV
dc.relation.ispartofseriesInternational journal of adhesion and adhesives
dc.relation.urihttp://dx.doi.org/10.1016/j.ijadhadh.2019.01.003
dc.rightsCC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectdimethyl sulfoxide
dc.subjectethanol
dc.subjectdemineralized dentin
dc.subjectdentin collagen
dc.subjectHEMA
dc.titleInfluence of polar solvents on permeability, stiffness and collagen dissociation of demineralized dentin
dc.description.versionfinal draft
dc.contributor.departmentSchool of Medicine / Dentistry
uef.solecris.id60817881en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Elsevier Ltd.
dc.relation.doi10.1016/j.ijadhadh.2019.01.003
dc.description.reviewstatuspeerReviewed
dc.format.pagerange148-153
dc.relation.issn0143-7496
dc.relation.volume89
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessEi


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