Show simple item record

dc.contributor.authorAarnio, Emma
dc.contributor.authorHuupponen, Risto
dc.contributor.authorMartikainen, Jaana E
dc.contributor.authorKorhonen, Maarit J
dc.date.accessioned2020-04-06T10:03:57Z
dc.date.available2020-04-06T10:03:57Z
dc.date.issued2020
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/8083
dc.description.abstractBackground Since 1994, the Finnish Prescription Register (FPR) has been the main data source for pharmacoepidemiology research in Finland. However, the FPR data are limited to reimbursed dispensations only. Implementation of electronic prescribing started in 2010 and after a stepwise extension, electronic prescribing became mandatory in all healthcare settings in 2017. Prescriptions issued and dispensed electronically are stored in the Prescription Centre of the nationwide Kanta database. Objectives To describe the contents of the Kanta database and to compare the coverage of Kanta with the FPR, using prescriptions and dispensations of oral anticoagulants (OACs) as an example. Methods All prescriptions, dispensations, and their cancellations and corrections for OACs recorded in Kanta were retrieved for the period 2012–2016. Results In 2016, the total number of valid electronic prescriptions for OACs was 249 139 and the number of valid electronic OAC dispensations was 765 745. The number of identified direct oral anticoagulant (DOAC) users was higher in Kanta compared to the FPR since 2014, although more users of all OACs were identified from the FPR during 2012–2015. In 2016, an indication was identified in 44.7% of OAC prescriptions and dosing instructions in 99.5% of DOAC prescriptions. Conclusions The Kanta database is a promising source of data on medication exposure. Because of reimbursement restrictions, use of DOACs was under-ascertained through the FPR.
dc.language.isoenglanti
dc.publisherElsevier BV
dc.relation.ispartofseriesResearch in social and administrative pharmacy
dc.relation.urihttp://dx.doi.org/10.1016/j.sapharm.2019.06.012
dc.rightsCC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectelectronic prescribing
dc.subjectdatabase
dc.subjectoral anticoagulants
dc.titleFirst insight to the Finnish nationwide electronic prescription database as a data source for pharmacoepidemiology research
dc.description.versionfinal draft
dc.contributor.departmentSchool of Pharmacy, Activities
uef.solecris.id63364131en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Elsevier Inc.
dc.relation.doi10.1016/j.sapharm.2019.06.012
dc.description.reviewstatuspeerReviewed
dc.format.pagerange553-559
dc.relation.issn1551-7411
dc.relation.issue4
dc.relation.volume16
dc.rights.accesslevelopenAccess
dc.type.okmA1
uef.solecris.openaccessEi


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record