Browsing by Author "Dennis, J"

Now showing items 1-3 of 3

    • Genetic predisposition to ductal carcinoma in situ of the breast 

      Petridis, C; Brook, MN; Shah, V; Kohut, K; Gorman, P; Caneppele, M; Levi, D; Papouli, E; Orr, N; Cox, A; Cross, SS; Dos-Santos-Silva, I; Peto, J; Swerdlow, A; Schoemaker, MJ; Bolla, MK; Wang, Q; Dennis, J; Michailidou, K; Benitez, J et al (Springer Nature, 2016)
      Background Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. It is often associated with invasive ductal carcinoma (IDC), and is considered to be a non-obligate precursor of IDC. It is not clear to ...
      info:eu-repo/semantics/article

    • Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus 

      Zeng, C; Guo, X; Long, J; Kuchenbaecker, KB; Droit, A; Michailidou, K; Ghoussaini, M; Kar, S; Freeman, A; Hopper, JL; Milne, RL; Bolla, MK; Wang, Q; Dennis, J; Agata, S; Ahmen, S; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Antonenkova, NN et al (BioMed Central Ltd, 2016)
      Background Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated with breast cancer risk. Method We performed a fine-scale ...
      info:eu-repo/semantics/article

    • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes 

      Mavaddat, N; Michailidou, K; Dennis, J; Lush, M; Fachal, L; Lee, A; Tyrer, JP; Chen, TH; Wang, Q; Bolla, MK; Yang, X; Adank, MA; Ahearn, T; Aittomäki, K; Allen, J; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Arndt, V; Aronson KJ; et al. [Incl Auvinen, Päivi; Kataja, Vesa; Kosma, Veli-Matti; Mannermaa, Arto] (Elsevier BV, 2019)
      Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, optimized for prediction of estrogen ...
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